Browsing by Subject "'de novo' viral quasispecies assembly"

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    • Inference of viral quasispecies with a paired de Bruijn graph 

      Freire, Borja; Ladra, Susana; Paramá, José R.; Salmela, Leena (Oxford University Press, 2021-02)
      [Abstract]: Motivation: RNA viruses exhibit a high mutation rate and thus they exist in infected cells as a population of closely related strains called viral quasispecies. The viral quasispecies assembly problem asks to ...

    • ViQUF: De Novo Viral Quasispecies Reconstruction Using Unitig-Based Flow Networks 

      Freire, Borja; Ladra, Susana; Paramá, José R.; Salmela, Leena (Institute of Electrical and Electronics Engineers, Association for Computing Machinery, Computational Intelligence Society, Control Systems Society, Engineering in Medicine and Biology Society, 2023-03)
      [Abstract]: During viral infection, intrahost mutation and recombination can lead to significant evolution, resulting in a population of viruses that harbor multiple haplotypes. The task of reconstructing these haplotypes ...