Browsing by Research Group "Enfermidades Cerebrovasculares: Neuroloxía Clínica e Traslacional (INIBIC)"
Now showing items 1-20 of 56
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A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment
(Elsevier, 2023-12-15)[Abstract] Background: Thrombolytic recombinant tissue plasminogen activator (r-tPA) treatment is the only pharmacologic intervention available in the ischemic stroke acute phase. This treatment is associated with an ... -
A predictive clinical-genetic model of tissue plasminogen activator response in acute ischemic stroke
(John Wiley & Sons, 2012-06-09)[Abstract] Objective: Wide interindividual variability exists in response to tissue plasminogen activator (t-PA) treatment in the acute phase of ischemic stroke. We aimed to find genetic variations associated with hemorrhagic ... -
A randomized trial on hemodynamic optimization of cerebral perfusion after successful endovascular therapy in patients with acute ischemic stroke (HOPE)
(Karger, 2024-08-29)[Abstract] Introduction: In patients with acute ischemic stroke (AIS) secondary to intracranial large vessel occlusion, optimal blood pressure (BP) management following endovascular treatment (EVT) has not yet been ... -
Association of high serum levels of growth factors with good outcome in ischemic stroke: a multicenter study
(Springer Nature, 2019-11-25)[Abstract] The main objective of this research work was to study the association of serum levels of growth factors (GF) and SDF-1α with the functional outcome and reduction of lesion volume in ischemic stroke patients. In ... -
Blood biomarker panels for the early prediction of stroke‐associated complications
(American Heart Association, 2021-02-26)[Abstract] Background. Acute decompensated heart failure (ADHF) and respiratory tract infections (RTIs) are potentially life‐threatening complications in patients experiencing stroke during hospitalization. We aimed to ... -
Blood biomarkers predictive of epilepsy after an acute stroke event
(John Wiley & Sons, 2020-08-28)[Abstract] Objective: Blood biomarkers have not been widely investigated in poststroke epilepsy. In this study, we aimed to describe clinical factors and biomarkers present during acute stroke and analyze their association ... -
Cav-1 protein levels in serum and infarcted brain correlate with hemorrhagic volume in a mouse model of thromboembolic stroke, independently of rt-PA administration
(Springer Nature, 2022-01-05)[Abstract] Thrombolytic therapy with recombinant tissue plasminogen activator (rt-PA) is currently the only FDA-approved drug for acute ischemic stroke. However, its administration is still limited due to the associated ... -
Cerebral hemodynamic reserve and early neurologic deterioration in acute ischemic stroke
(Sage, 2004-11)[Abstract] Early neurological deterioration (END) is associated with increased mortality and morbidity. Although several predictive factors have been reported, there are little data about the hemodynamic factors. Our aim ... -
Characteristics of stroke units and stroke teams in Spain in 2018: Pre2Ictus project
(Elsevier, 2022-06-30)[Abstract] Introduction: The aim of this work is to describe the characteristics of stroke units and stroke teams in Spain. Method: We performed a cross-sectional study based on an ad hoc questionnaire designed by ... -
Comentario del CEIPV a las nuevas Guías Europeas de Prevención Cardiovascular 2021
(Elsevier en nombre de la Sociedad Española de Nefrología, 2022-06-10)[Resumen] Presentamos la adaptación española de las Guías Europeas de Prevención Cardiovascular 2021. En esta actualización además del abordaje individual, se pone mucho más énfasis en las políticas sanitarias como estrategia ... -
Decreased corticospinal tract fractional anisotropy predicts long-term motor outcome after stroke
(American Heart Association, 2013-05-07)[Abstract] Background and purpose: Nearly 50% of patients have residual motor deficits after stroke, and long-term motor outcome is difficult to predict. We assessed the predictive value of axonal damage to the corticospinal ... -
Delayed neurological improvement after full endovascular reperfusion in acute anterior circulation ischemic stroke
(American Heart Association, 2021-05-20)[Abstract] Background and purpose: We aimed to determine the prevalence and predictors of delayed neurological improvement (DNI) after complete endovascular reperfusion in anterior circulation acute ischemic stroke ... -
Depression in major neurodegenerative diseases and strokes: a critical review of similarities and differences among neurological disorders
(MDPI, 2023-02-13)[Abstract] Depression and anxiety are highly prevalent in most neurological disorders and can have a major impact on the patient’s disability and quality of life. However, mostly due to the heterogeneity of symptoms and ... -
Documento de consenso de la Sociedad Española de Ginecología y Obstetricia (SEGO) y el Comité Español Interdisciplinario para la Prevención Vascular (CEIPV): ventana de oportunidad: prevención del riesgo vascular en la mujer: resultados adversos del embarazo y riesgo de enfermedad vascular
(Sociedad Española de Ginecología y Obstetricia (SEGO), 2023)[Resumen] Este documento resume la evidencia que existe entre los resultados adversos del embarazo (RAE), tales como son los trastornos hipertensivos, el parto pretérmino, la diabetes gestacional, los defectos en el ... -
Documento de consenso para la determinación e informe del perfil lipídico en laboratorios clínicos españoles: ¿qué parámetros debe incluir un perfil lipídico básico?
(Elsevier, 2023-03-14)[Resumen] Las enfermedades cardiovasculares (ECV) siguen siendo la principal causa de muerte en nuestro país. El control adecuado de las alteraciones del metabolismo lipídico es un reto clave en prevención cardiovascular ... -
Dyslipidemias and stroke prevention: recommendations of the Study Group of Cerebrovascular Diseases of the Spanish Society of Neurology
(Elsevier, 2022-01)[Abstract] Objective: We present an update of the Spanish Society of Neurology's recommendations for prevention of both primary and secondary stroke in patients with dyslipidaemia. Development: We performed a ... -
Embolism in acute middle cerebral artery stenosis
(Wolters Kluwer, 2001-02-27)[Abstract] Objective: To investigate the frequency of middle cerebral artery (MCA) stenosis in a series of nonselected patients and the coexistence of microembolic signals with stenosis. Methods: MCA stenosis was ... -
Estudio de la situación actual del Teleictus en España
(Elsevier, 2023-08-07)[Resumen] Introducción. En los últimos años se ha establecido el uso del Teleictus como una herramienta fundamental para extender la atención a los pacientes con ictus agudo hasta hospitales que no disponen de neurólogos ... -
High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke
(American Academy of Neurology, 2008-12-02)[Abstract] Background: Excitotoxic and inflammatory mechanisms have been demonstrated as mediating early neurologic deterioration (END) in patients with cerebral infarction. Here we investigate whether molecular markers ... -
Impact of coronavirus disease 2019 pandemic on Parkinson's disease: a cross-sectional survey of 568 spanish patients
(John Wiley & Sons, 2020-09-22)[Abstract] Background: The aim of this study was to know the impact of the coronavirus disease 2019 (COVID-19) pandemic on Spanish patients with Parkinson's disease (PD). Methods: This is a descriptive, observational, ...