Browsing by Research Group "Diagnóstico Condutual e Molecular Aplicado á Saúde (DICOMOSA)"
Now showing items 1-20 of 51
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La adolescencia vista desde la epigenética
(Universidade da Coruña, 2019)[Resumen] La adolescencia es el proceso en donde se produce la transformación de niño en adulto, por tanto, es un período de transición crítico e intenso, que tiene características peculiares como la inestabilidad y el ... -
Analysis of Four Polymorphisms Located at the Promoter of the Estrogen Receptor Alpha ESR1 Gene in a Population With Gender Incongruence
(2020)[Abstract] Introduction: Gender incongruence defines a state in which individuals feel discrepancy between the sex assigned at birth and their gender. Some of these people make a social transition from male to female ... -
Applicability of EU(7)-PIM criteria in cross-national studies in European countries
(2019)[Abstract] Background: The European Union (EU)(7)-PIM (potentially inappropriate medication) list presents the most comprehensive and up-to-date tool for evaluation of PIM prescribing in Europe; however, several ... -
Assessing the in Vitro Toxicity of Airborne (Nano)Particles to the Human Respiratory System: From Basic to Advanced Models [Review]
(Taylor & Francis, 2023-01-24)[Abstract] Several studies have been conducted to address the potential adverse health risks attributed to exposure to nanoscale materials. While in vivo studies are fundamental for identifying the relationship between ... -
Assessment of Okadaic Acid Effects on Cytotoxicity, DNA Damage and DNA Repair in Human Cells
(Elsevier, 2010-05-26)[Abstract] Okadaic acid (OA) is a phycotoxin produced by several types of dinoflagellates causing diarrheic shellfish poisoning (DSP) in humans. Symptoms induced by DSP toxins are mainly gastrointestinal, but the intoxication ... -
Association Between Cognitive Reserve Proxies and Frailty Phenotype: Data from UK Biobank
(Springer Nature, 2024-10-14)[Abstract] A potential protective role of cognitive reserve proxies against frailty has been suggested in older adults. We explored the cross-sectional association between cognitive reserve indicators and frailty phenotype. ... -
Atención sanitaria en España a personas transexuales y con variantes de género: historia y evolución
(Singlantana, 2019-10)[Resumen] Objetivos: El objetivo de este artículo es analizar cronológicamente los inicios y evolución de la atención sanitaria en España a la transexualidad y variantes de género. Metodología: Se realiza un estudio ... -
CBLL1 is hypomethylated and correlates with cortical thickness in transgender men before gender affirming hormone treatment
(Springer Nature, 2023-12)[Abstract] Gender identity refers to the consciousness of being a man, a woman or other condition. Although it is generally congruent with the sex assigned at birth, for some people it is not. If the incongruity is ... -
Comparative Study of Human Neuronal and Glial Cell Sensitivity for in Vitro Neurogenotoxicity Testing
(Elsevier, 2017-02-03)[Abstract] Cell cultures from neuronal and glial origin have proven to be powerful tools for elucidating cellular and molecular mechanisms of nervous system development and physiology, and as neurotoxicity models to evaluate ... -
Comparative Study on Effects of Two Different Types of Titanium Dioxide Nanoparticles on Human Neuronal Cells
(Elsevier, 2013-04-15)[Abstract] Titanium dioxide (TiO2) are among most frequently used nanoparticles (NPs). They are present in a variety of consumer products, including food industry in which they are employed as an additive. The potential ... -
Cytogenetic Effects Induced by Prestige Oil on Human Populations: The Role of Polymorphisms in Genes Involved in Metabolism and DNA Repair
(Elsevier, 2008-04-18)[Abstract] The spill from the oil tanker Prestige (NW Spain, November 2002) was perhaps the biggest ecological disaster that happened worldwide in the last decades. As a consequence of this catastrophe a general concern ... -
DNA Damage in Circulating Leukocytes Measured With the Comet Assay May Predict the Risk of Death
(2021)[Abstract] The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, ... -
Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis
(Multidisciplinary Digital Publishing Institute, 2016)Okadaic acid (OA) and dinophysistoxins (DTXs) are the main toxins responsible for diarrhetic shellfish poisoning (DSP) intoxications during harmful algal blooms (HABs). Although the genotoxic and cytotoxic responses to OA ... -
Editorial: Research in Transgender Healthcare: What Have We Learned and Where Are We Going?
(2022)[Abstract] Gender incongruence (GI) is defined as “an individual’s discontent with their assigned gender and their identification with a gender other than that associated with their birth sex based on physical sex ... -
Efectos de la terapia asistida con animales en personas con daño cerebral o lesión medular
(Fundación MAPFRE, 2013-04)[Resumen] Objetivo: Valorar los efectos terapéuticos obtenidos al aplicar un programa de terapia asistida con animales (TAA) en personas con daño cerebral o lesión medular. Material y método: Se realizó un estudio ... -
Effects of Iron Oxide Nanoparticles: Cytotoxicity, Genotoxicity, Developmental Toxicity, and Neurotoxicity
(Wiley, 2014-08-22)[Abstract] Iron oxide nanoparticles (ION) with superparamagnetic properties hold great promise for use in various biomedical applications; specific examples include use as contrast agents for magnetic resonance imaging, ... -
Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos
(MDPI, 2023-08-01)[Abstract] Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use ... -
Endocrine and Immunological Parameters in Individuals Involved in Prestige Spill Cleanup Tasks Seven Years After the Exposure
(Elsevier, 2013-06-20)[Abstract] In November 2002 the oil tanker Prestige spilled 63,000tonnes of heavy oil off the northwest coast of Spain, impacting more than 1000km of coastline. A general concern led to a huge mobilization of human and ... -
Epigenetics Is Implicated in the Basis of Gender Incongruence: An Epigenome-Wide Association Analysis
(2021)[Abstract] Introduction: The main objective was to carry out a global DNA methylation analysis in a population with gender incongruence before gender-affirming hormone treatment (GAHT), in comparison to a cisgender ...
