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    • Safety and efficacy of ApTOLL in patients with ischemic stroke undergoing endovascular treatment: a phase 1/2 randomized clinical trial 

      Hernández-Jiménez, Macarena; Abad-Santos, Francisco; Cotgreave, Ian; Gallego, Jaime; Jilma, Bernd; Flores, Alan; Jovin, Tudor G.; Vivancos, José; Hernández-Pérez, María; Molina, Carlos A.; Montaner, Joan; Casariego, Joaquín; Dalsgaard, Mads; Liebeskind, David S.; Cobo, Erik; Castellanos, María del Mar; Cardona Portela, Pere; Masjuán, Jaime; Moniche, Francisco; Tembl, José Ignacio; Terceño Izaga, Mikel; Arenillas, Juan; Calleja, Patricia; Olivot, Jean Marc; Calviere, Lionel; Henon, Hilde; Mazighi, Mikael; Piñeiro, David; Pugliese, Marco; González, Víctor M.; Moro, María Ángeles; García-Tornel, Álvaro; Lizasoain, Ignacio; Ribo, Marc (American Medical Association, 2023-06-20)
      [Abstract] Importance: ApTOLL is a TLR4 antagonist with proven preclinical neuroprotective effect and a safe profile in healthy volunteers. Objective: To assess the safety and efficacy of ApTOLL in combination with ...