Browsing by Research Group "Enfermidades Cerebrovasculares: Neuroloxía Clínica e Traslacional (INIBIC)"

Now showing items 21-40 of 56

    • Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain 

      Tejada Meza, Herbert; Lambea Gil, Álvaro; Sancho Saldaña, Agustín; Martínez-Zabaleta, Maite; de la Riva, Patricia; López-Cancio Martínez, Elena; Castañón Apilánez, María; Herrera Isasi, María; Marta Enguita, Juan; Lera Alfonso, Mercedes de; Arenillas, Juan; Segurola Olaizaola, Jon; Timiraos Fernández, Juan José; Sánchez, Joaquín; Castellanos, María del Mar; Roel, Alexia; Casado Menéndez, Ignacio; Freijo Guerrero, María del Mar; Luna, Alain; Palacio-Portilla, Enrique Jesús; Jiménez López, Yésica; Rodríguez Castro, Emilio; Arias Rivas, Susana; Tejada García, Javier; Beltrán Rodríguez, Iria; Julián Villaverde, Francisco; Moreno García, María Pilar; Trejo-Gabriel-Galán, José María; Echevarría Íñiguez, Ana; Tejero Juste, Carlos; Pérez Lázaro, Cristina; Marta Moreno, Javier (Sage, 2020-06-11)
      [Abstract] Background and purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital ...

    • Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain 

      Tejada Meza, Herbert; Lambea Gil, Álvaro; Sancho Saldaña, Agustín; Martínez-Zabaleta, Maite; Riva Juez, Patricia de la; López-Cancio Martínez, Elena; Castañón Apilánez, María; Herrera Isasi, María; Marta Enguita, Juan; Lera Alfonso, Mercedes de; Arenillas, Juan; Segurola Olaizola, Jon; Timiraos Fernández, Juan José; Sánchez, Joaquín; Castellanos, María del Mar; Roel, Alexia; Casado Menéndez, Ignacio; Freijo Guerrero, María del Mar; Luna Rodríguez, Alain; Palacio Portilla, Enrique; Jiménez López, Yésica; Rodríguez Castro, Emilio; Arias Rivas, Susana; Tejada García, Javier; Beltrán Rodríguez, Iria; Julián-Villaverde, Francisco; Moreno García, María Pilar; Trejo-Gabriel-Galán, José María; Echevarría Íñiguez, Ana; Tejero Juste, Carlos; Pérez Lázaro, Cristina; Marta Moreno, Javier (Sage, 2020-06-11)
      [Abstract] Background and purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital ...

    • Impact of mediterranean diet prior to stroke on the prognosis of patients undergoing endovascular treatment 

      García-Cabo, Carmen; Castañón Apilánez, María; Benavente-Fernández, Lorena; Jiménez, José María; Arenillas, Juan; Castellanos, María del Mar; Rodrigo-Stevens, Gabriela; Tejada Meza, Herbert; Pérez, Cristina; Martínez-Zabaleta, Maite; Rodríguez-Castro, Emilio; Sánchez, Joaquín; Julián-Villaverde, Francisco; Pinedo Brochado, Ana; Palacio, Enrique; López-Cancio Martínez, Elena (Karger, 2021-03-17)
      [Abstract] Introduction: Mediterranean diet (MeDiet) has been associated with lower risk of stroke. Additionally, animal models suggested that some components of MeDiet are associated with better outcomes after ischemic ...

    • Increased plasma levels of 15-deoxyDelta prostaglandin J2 are associated with good outcome in acute atherothrombotic ischemic stroke 

      Blanco, Miguel; Moro, María Ángeles; Dávalos, Antonio; Leira, Rogelio; Castellanos, María del Mar; Serena, Joaquín; Vivancos, José; Rodríguez-Yáñez, Manuel; Lizasoain, Ignacio; Castillo, José (American Heart Association, 2005-05-05)
      [Abstract] Background and purpose: The 15-deoxyDelta prostaglandin J2 (15-dPGJ2) is an anti-inflammatory prostaglandin that has been proposed to be the endogenous ligand of peroxisome proliferator-activated receptor-gamma ...

    • Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target 

      Castellanos, María del Mar; Castillo, José; García, María M.; Leira, Rogelio; Serena, Joaquín; Chamorro, Ángel; Dávalos, Antoni (American Heart Association, 2002-04-01)
      [Abstract] Background and purpose: The mechanisms underlying neurological deterioration in patients with lacunar infarction are not completely understood. In this study, we sought to investigate the role of proinflammatory ...

    • Liquid chromatography fingerprint analysis of released compounds in plasmas samples of stroke patients after thrombolytic treatment 

      Castellanos, María del Mar; Fernández-Couto, Dolores; Da Silva-Candal, Andrés; Rodríguez-Yáñez, Manuel; Gubern-Mérida, Carmen; Sánchez, Juan M.; Feal-Painceiras, María J. (MDPI, 2023-01-05)
      [Abstract] Plasma samples obtained from stroke patients treated with recombinant tissue-type plasminogen activator (rt-PA) and not treated with rt-PA were evaluated with different HPLC methodologies to obtain information ...

    • Mechanical thrombectomy with the Solitaire AB device in large artery occlusions of the anterior circulation: a pilot study 

      Castaño, Carlos; Dorado, Laura; Guerrero, Cristina; Millán, Mónica; Gomis, Meritxell; Pérez de la Ossa, Natalia; Castellanos, María del Mar; García, María Rosa; Domenech, Sira; Dávalos, Antoni (American Heart Association, 2010-06-10)
      [Abstract] Background and purpose: To describe the safety and effectiveness of a self-expanding and fully retrievable stent (Solitaire AB; ev3 Inc, Plymouth, MN) in revascularization of patients with acute ischemic ...

    • Microembolic signal monitoring in hemispheric acute ischaemic stroke: a prospective study 

      Serena, Joaquín; Segura, Tomás; Castellanos, María del Mar; Dávalos, Antoni (Karger, 2000-06-22)
      [Abstract] Background and purpose: There are few data on the occurrence of microembolic signals (MES) in the acute phase of ischaemic stroke. The objective of our work was to systematically study the frequency of MES ...

    • MiRNA expression is modulated over time after focal ischaemia: up-regulation of miR-347 promotes neuronal apoptosis 

      Gubern-Mérida, Carme; Camós, Susanna; Ballesteros, Iván; Rodríguez, Rocío; Romera, Víctor G.; Cañadas, Roberto; Lizasoain, Ignacio; Moro, María Ángeles; Serena, Joaquín; Mallolas, Judith; Castellanos, María del Mar (FEBS Press, 2013-10-01)
      [Abstract] Despite the large number of molecules reported as being over-expressed after ischaemia, little is known regarding their regulation. miRNAs are potent post-transcriptional regulators of gene expression, and reports ...

    • Oral anticoagulation and risk of symptomatic hemorrhagic transformation in stroke patients treated with mechanical thrombectomy: data from the nordictus registry 

      Ramos-Araque, María E.; Chavarría-Miranda, Alba; Gómez-Vicente, Beatriz; López-Cancio Martínez, Elena; Castañón Apilánez, María; Castellanos, María del Mar; López Fernández, María; Tejada Meza, Herbert; Marta Moreno, Javier; Tejada García, Javier; Beltrán Rodríguez, Iria; de la Riva, Patricia; Díez, Noemí; Arias Rivas, Susana; Santamaría Cadavid, María; Bravo Anguiano, Yolanda; Bártulos Iglesias, Mónica; Palacio-Portilla, Enrique Jesús; Revilla García, Marian; Timiraos Fernández, Juan José; Arenaza Basterrechea, Naroa; Maciñeiras Montero, José Luis; Vicente Alba, Pablo; Julián Villaverde, Francisco José; Pinedo Brochado, Ana; Azkune, Itxaso; Freijo Guerrero, María del Mar; Luna, Alain; Arenillas, Juan (Frontiers, 2020-11-26)
      [Abstract] Introduction: We aimed to evaluate if prior oral anticoagulation (OAC) and its type determines a greater risk of symptomatic hemorrhagic transformation in patients with acute ischemic stroke (AIS) subjected to ...

    • Perceptions of key informant neurologists before implementing anti-amyloid drugs in the Spanish departments of neurology 

      Matias-Guiu, Jordi A.; Álvarez-Sabín, José; Botia, Enrique; Casado-Naranjo, Ignacio; Castellanos, María del Mar; Frank, Ana; Íñiguez, Cristina; Jiménez-Hernández, María Dolores; Jiménez-Jiménez, Félix Javier; Láinez, José-Miguel; Moral, Ester; Pérez-Martínez, David A.; Rodríguez-Antigüedad, Alfredo; Ruiz-Lavilla, Nuria; Segura, Tomás; Serrano-Castro, Pedro J.; Matias-Guiu, Jorge (Sage, 2024-10-28)
      [Abstract] Background: A deep knowledge of the healthcare system and the organization of neurology departments is important for planning and optimizing changes to facilitate the successful implementation of anti-amyloid ...

    • Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke 

      Castellanos, María del Mar; Leira, Rogelio; Serena, Joaquín; Pumar, José Manuel; Lizasoain, Ignacio; Castillo, José; Dávalos, Antoni (American Heart Association, 2002-12-05)
      [Abstract] Background and purpose: Matrix metalloproteinase-9 (MMP-9) activity has been associated with hemorrhagic transformation (HT) in experimental models of cerebral ischemia. Our aim was to investigate the relationship ...

    • Pre-existing cerebral small vessel disease limits early recovery in patients with acute lacunar infarct 

      Gómez-Choco, Manuel; Mengual, Juan José; Rodríguez-Antigüedad, Jon; Paré-Curell, Martí; Purroy, Francisco; Palomeras, Ernest; Fuentes, Blanca; Ustrell, Xavier; Tembl, José; Rodríguez-Yáñez, Manuel; Castellanos, María del Mar; Martí-Fábregas, Joan; Serena, Joaquín (Elsevier, 2019-11)
      [Abstract] Background and purpose: To assess whether neuroimaging markers of chronic cerebral small vessel disease (cSVDm) influence early recovery after acute ischemic stroke (AIS). Methods: Retrospective analysis ...

    • Preclinical validation of human recombinant glutamate-oxaloacetate transaminase for the treatment of acute ischemic stroke 

      Pérez-Mato, María; Dopico-López, Antonio; Akkoc, Yunus; López-Amoedo, Sonia; Correa-Paz, Clara; Candamio-Lourido, María; Iglesias-Rey, Ramón; López-Arias, Esteban; Bugallo-Casal, Ana; da Silva-Candal, Andrés; Bravo, Susana B.; Chantada-Vázquez, María del Pilar; Arias, Susana; Santamaría-Cadavid, María; Estany-Gestal, Ana; Zagmi, Ahlem; Gauthier, Marc A.; Gutiérrez-Fernández, María; Martin, Abraham; Llop, Jordi; Rodríguez, Cristina; Almeida, Ángeles; Migliavacca, Martina; Polo, Ester; Pelaz, Beatriz; Gozuacik, Devrim; El Yamani, Naouale; SenGupta, Tanima; Rundén-Pran, Elise; Vivancos, José; Castellanos, María del Mar; Díez-Tejedor, Exuperio; Sobrino, Tomás; Rabinkov, Aharon; Mirelman, David; Castillo, José; Campos, Francisco (Cell Press, 2024-11-15)
      [Summary] The blood enzyme glutamate-oxaloacetate transaminase (GOT) has been postulated as an effective therapeutic to protect the brain during stroke. To demonstrate its potential clinical utility, a new human recombinant ...

    • Prevención de ictus en pacientes con diabetes mellitus tipo 2 o prediabetes: recomendaciones del Grupo de Estudio de Enfermedades Cerebrovasculares de la Sociedad Española de Neurología 

      Fuentes, Blanca; Amaro, Sergio; Alonso de Ceciñana, María; Arenillas, Juan; Ayo-Martín, Óscar; Castellanos, María del Mar; Freijo Guerrero, María del Mar; García Pastor, Andrés; Gomis, Meritxell; Gómez Choco, Manuel; López-Cancio Martínez, Elena; Martínez Sánchez, Patricia; Morales, Ana; Palacio-Portilla, Enrique Jesús; Rodríguez-Yáñez, Manuel; Roquer, Jaume; Segura, Tomás; Serena, Joaquín; Vivancos-Mora, José (Elsevier, 2020-09-24)
      [Resumen] Objetivo. Actualizar las recomendaciones de la Sociedad Española de Neurología para la prevención del ictus en pacientes con DM-2 o prediabetes, analizando las evidencias disponibles sobre el efecto del control ...

    • Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: consensus document and practice guidance 

      Gil-Núñez, Antonio; Masjuan, Jaime; Montaner, Joan; Castellanos, María del Mar; Segura, Tomás; Cardona, Pere; Tembl, José Ignacio; Purroy, Francesc; Arenillas, Juan; Palacio, Enrique (Elsevier, 2021-12-11)
      [Abstract] Introduction: Patients with history of stroke or transient ischaemic attack present considerable risk of future vascular events. Reducing levels of low-density lipoprotein (LDL) cholesterol decreases the ...

    • Recommendations of the Spanish Society of Neurology for the prevention of stroke: interventions on lifestyle and air pollution 

      García Pastor, Andrés; López-Cancio Martínez, Elena; Rodríguez-Yáñez, Manuel; Alonso de Ceciñana, María; Amaro, Sergio; Arenillas, Juan; Ayo-Martín, Óscar; Castellanos, María del Mar; Fuentes, Blanca; Freijo Guerrero, María del Mar; Gomis, Meritxell; Gómez Choco, Manuel; Martínez Sánchez, Patricia; Morales, Ana; Palacio-Portilla, Enrique Jesús; Segura, Tomás; Serena, Joaquín; Vivancos-Mora, José; Roquer, Jaume (Elsevier, 2021-03-27)
      [Abstract] Objective: To update the recommendations of the Spanish Society of Neurology regarding lifestyle interventions for stroke prevention. Development: We reviewed the most recent studies related to lifestyle ...

    • Recommendations on the use of computed tomography in the stroke code: Consensus document SENR, SERAU, GEECV-SEN, SERAM 

      López-Rueda, Antonio; Ibáñez Sanz, Laín; Alonso de Leciñana, María; Araújo Martins-Romeo, Daniela de; Vicente Bártulos, Agustina; Castellanos, María del Mar; Oleaga Zufiria, Laura (Elsevier, 2023-03-29)
      [Abstract] The Spanish Society of Emergency Radiology (SERAU), the Spanish Society of Neuroradiology (SENR), the Spanish Society of Neurology through its Cerebrovascular Diseases Study Group (GEECV-SEN) and the Spanish ...

    • Retos principales a corto y medio plazo en el ictus 

      Castellanos, María del Mar (Permanyer, 2022-05-28)

    • RP11-362K2.2:RP11-767I20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma: a GWAS meta-analysis 

      Muiño, Elena; Cárcel-Márquez, Jara; Carrera, Caty; Llucià-Carol, Laia; Gallego-Fábrega, Cristina; Cullel, Natalia; Lledós, Miquel; Castillo, José; Sobrino, Tomás; Campos, Francisco; Rodríguez-Castro, Emilio; Millán, Mónica; Muñoz-Narbona, Lucía; Bustamante, Alejandro; López-Cancio Martínez, Elena; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Giralt-Steinhauer, Eva; Soriano-Tárraga, Carolina; Vives-Bauza, Cristófol; Díaz Navarro, Rosa; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fàbregas, Joan; Delgado-Mederos, Raquel; Camps-Renom, Pol; Prats-Sánchez, Luis; Guisado, Daniel; Guasch, Marina; Marin, Rebeca; Martínez-Domeño, Alejandro; Freijo Guerrero, María del Mar; Moniche Álvarez, Francisco; Cabezas, Juan Antonio; Castellanos, María del Mar; Krupinsky, Jerzy; Strbian, Daniel; Tatlisumak, Turgut; Thijs, Vincent; Lemmens, Robin; Slowik, Agnieszka; Pera, Joanna; Heitsch, Laura; Ibáñez, Laura; Cruchaga, Carlos; Dhar, Rajat; Lee, Jin-Moo; Montaner, Joan; Fernández-Cadenas, Israel (MDPI, 2021-07-16)
      [Abstract] Stroke is one of the most common causes of death and disability. Reperfusion therapies are the only treatment available during the acute phase of stroke. Due to recent clinical trials, these therapies may increase ...