Browsing Síntese Asimétrica by Issue Date
Now showing items 1-6 of 6
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Stereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim ethers
(The Royal Society of Chemistry, 2002-06-25)[Abstract] Electrophilic fluorinations of lithiated bis-lactim ethers derived from cyclo-[L-AP4-D-Val] allow a direct access to alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, ... -
Diastereoselective Synthesis of Piperidine Imino Sugars Using Aldol Additions of Metalated Bislactim Ethers to Threose and Erythrose Acetonides
(American Chemical Society, 2008-02-27)[Abstract] A general strategy for the synthesis of 1-deoxy-azasugars from a chiral glycine equivalent and 4-carbon building blocks is described. Diastereoselective aldol additions of metalated bislactim ethers to matched ... -
Access to Pyrrolidine Imino Sugars via Tin(II)-Mediated Aldol Reactions of Bislactim Ethers: Synthesis of 2,5-Dideoxy-2,5-Imino-D-Glucitol
(Royal Society of Chemistry, 2008-09-05)[Abstract] 2,5-Dideoxy-2,5-imino-D-glucitol (DGDP) has been synthesized via the tin(II)-mediated anti-selective aldol reaction of bislactim ether 5 and a 3-O-silylated 2,4-ethylidene-D-erythrose derivative 6. In accordance ... -
Synthesis of Pyrrolidine Homoazasugars and 3,4-Dihydroxy-5-Hydroxymethylprolines Using Aldol Additions of Metalated Bislactim Ethers to 2,4-O-Ethylidene-D-Erythroses
(Royal Society of Chemistry, 2009-03-27)[Abstract] A strategy for the synthesis of 2,5-dideoxy-2,5-iminohexitols and 2,5-dideoxy-2,5-iminoglyconic acids is described by using diastereoselective aldol additions of metalated bislactim ethers to 2,4-O-ethylidene- ... -
Preparation and Characterization of Terdentate [C,N,N] Acetophenone and Acetylpyridine Hydrazone Platinacycles: A DFT Insight Into the Reaction Mechanism
(Royal Society of Chemistry, 2017-11-13)[Abstract] The reaction of N-ortho-chlorophenyl-substituted acetylpyridine hydrazones (a and d) with K2[PtCl4] (n-butanol/water, 100 °C) gave mononuclear complexes 1a and 1d with the ligands as [N,N] bidentate. In contrast, ... -
DLPNO-CCSD(T) and DFT Study of the Acetate-Assisted C–H Activation of Benzaldimine at [RuCl2(p-cymene)]2: The Relevance of Ligand Exchange Processes at Ruthenium(II) Complexes in Polar Protic Media
(Royal Society of Chemistry (Gran Bretaña), 2024-04-25)[Abstract] To gain mechanistic insights into the acetate-assisted cyclometallations of arylimines promoted by [RuCl2(p-cymene)]2 in polar protic media, DFT geometry optimizations (with M06 and ωB97X-D3 functionals and the ...
