Building-Scale Wastewater-Based Epidemiology for SARS-CoV-2 Surveillance at Nursing Homes in A Coruña, Spain
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Building-Scale Wastewater-Based Epidemiology for SARS-CoV-2 Surveillance at Nursing Homes in A Coruña, SpainAutor(es)
Fecha
2023-11Cita bibliográfica
Trigo-Tasende, N., Vallejo, J. A., Rumbo-Feal, S., Conde-Pérez, K., Nasser-Ali, M., Tarrío-Saavedra, J., et. al. (2023). Building-Scale Wastewater-Based Epidemiology for SARS-CoV-2 Surveillance at Nursing Homes in A Coruña, Spain. Environments 10(11). https://doi.org/10.3390/environments10110189
Resumen
[Abstract] Wastewater-based epidemiology (WBE) has become an effective tool in the surveillance of
infectious diseases such as COVID-19. In this work, we performed a brief study of monitoring the
SARS-CoV-2 viral load in wastewater from six nursing homes located in the metropolitan area of A
Coruña (Spain) between December 2020 and March 2021. The main objective was to detect SARSCoV-
2 outbreaks among residents and study the efficacy of the vaccination campaign. SARS-CoV-2
viral load (RNA copies per L of wastewater) was determined by reverse-transcription quantitative
PCR (RT-qPCR) using the quantification cycle (Cq) values for the nucleocapsid (N) gene. Our results
showed that the increase in viral load preceded the increase in clinical cases, favoring an early
warning system that detects COVID-19 outbreaks in advance, making it possible to contain and
stop the transmission of the virus among residents. In addition, the efficacy of the new COVID-19
vaccines was evidenced, since after the vaccination campaign in nursing homes in A Coruña, it was
observed that many residents did not present any symptoms of the disease, although they excreted
high amounts of virus in their feces. WBE is a cost-effective strategy that should be implemented in
all cities to prevent new emerging diseases or future pandemic threats.
Palabras clave
COVID-19
Epidemiology
Nursing home
Early warning
Environmental surveillance
Public health
Wastewater
SARS-CoV-2
WBE
Epidemiology
Nursing home
Early warning
Environmental surveillance
Public health
Wastewater
SARS-CoV-2
WBE
Descripción
Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG
Versión del editor
Derechos
Atribución 4.0 Internacional
ISSN
2076-3298