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Relevance of the extraction stage on the anti-inflammatory action of fucoidans
dc.contributor.author | Flórez-Fernández, Noelia | |
dc.contributor.author | Vaamonde-García, Carlos | |
dc.contributor.author | Torres, María Dolores | |
dc.contributor.author | Buján, Manuela | |
dc.contributor.author | Muíños, Alexandra | |
dc.contributor.author | Lamas-Vázquez, María J. | |
dc.contributor.author | Meijide-Faílde, Rosa | |
dc.contributor.author | Blanco García, Francisco J | |
dc.contributor.author | Domínguez, Herminia | |
dc.date.accessioned | 2023-04-17T07:33:59Z | |
dc.date.available | 2023-04-17T07:33:59Z | |
dc.date.issued | 2023-03-01 | |
dc.identifier.citation | Flórez-Fernández N, Vaamonde-García C, Torres MD, Buján M, Muíños A, Muiños A, Lamas-Vázquez MJ, Meijide-Faílde R, Blanco FJ, Domínguez H. Relevance of the extraction stage on the anti-inflammatory action of fucoidans. Pharmaceutics. 2023 Mar 1;15(3):808 | es_ES |
dc.identifier.issn | 1999-4923 | |
dc.identifier.uri | http://hdl.handle.net/2183/32876 | |
dc.description | Review | es_ES |
dc.description.abstract | [Abstract] The anti-inflammatory action of fucoidans is well known, based on both in vitro and some in vivo studies. The other biological properties of these compounds, their lack of toxicity, and the possibility of obtaining them from a widely distributed and renewable source, makes them attractive novel bioactives. However, fucoidans' heterogeneity and variability in composition, structure, and properties depending on seaweed species, biotic and abiotic factors and processing conditions, especially during extraction and purification stages, make it difficult for standardization. A review of the available technologies, including those based on intensification strategies, and their influence on fucoidan composition, structure, and anti-inflammatory potential of crude extracts and fractions is presented. | es_ES |
dc.description.sponsorship | This work was funded by the Ministry of Science and Innovation of Spain, research project CTM2012-38095, and postdoctoral grant RYC2018-024454-I; Xunta de Galicia (Centro Singular CINBIO, EDC431C/2022/08, ED431F 2020/01, ED481D-2022/018). | es_ES |
dc.description.sponsorship | info:eu-repo/grantAgreement/MINECO/Programa Nacional de Investigación Fundamental/CTM2012-38095/ES/ EXTRACCION Y PURIFICACION DE COMPUESTOS BIOACTIVOS DE SARGASSUM MUTICUM | |
dc.description.sponsorship | Ministerio de Ciencia e Innovación (España); RYC2018-024454-I | |
dc.description.sponsorship | Xunta de Galicia; EDC431C/2022/08 | |
dc.description.sponsorship | Xunta de Galicia; ED431F2020/01 | |
dc.description.sponsorship | Xunta de Galicia; ED481D-2022/018 | |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.relation.uri | https://doi.org/10.3390/pharmaceutics15030808 | es_ES |
dc.rights | Creative Commons Attribution 4.0 International Licence (CC-BY 4.0) | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Brown seaweed | es_ES |
dc.subject | Extraction | es_ES |
dc.subject | Inflammation | es_ES |
dc.subject | Sulphated polysaccharides | es_ES |
dc.title | Relevance of the extraction stage on the anti-inflammatory action of fucoidans | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
UDC.journalTitle | Pharmaceutics | es_ES |
UDC.volume | 15 | es_ES |
UDC.issue | 3 | es_ES |
UDC.startPage | 808 | es_ES |
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