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Biologically Active Peptides from Venoms: Applications in Antibiotic Resistance, Cancer, and Beyond [Review]
| dc.contributor.author | Ageitos, Lucía | |
| dc.contributor.author | Torres, M. D. T. | |
| dc.contributor.author | Fuente, César de la | |
| dc.date.accessioned | 2023-03-16T12:28:21Z | |
| dc.date.available | 2023-03-16T12:28:21Z | |
| dc.date.issued | 2022-12-06 | |
| dc.identifier.citation | Ageitos, L.; Torres, M.D.T.; de la Fuente-Nunez, C. Biologically Active Peptides from Venoms: Applications in Antibiotic Resistance, Cancer, and Beyond. Int. J. Mol. Sci. 2022, 23, 15437. https://doi.org/10.3390/ijms232315437 | es_ES |
| dc.identifier.issn | 1422-0067 | |
| dc.identifier.uri | http://hdl.handle.net/2183/32706 | |
| dc.description | This article belongs to the Special Issue Antimicrobial Peptides: Structure and Mechanism of Biological Activity 2.0 | es_ES |
| dc.description.abstract | [Abstract] Peptides are potential therapeutic alternatives against global diseases, such as antimicrobial-resistant infections and cancer. Venoms are a rich source of bioactive peptides that have evolved over time to act on specific targets of the prey. Peptides are one of the main components responsible for the biological activity and toxicity of venoms. South American organisms such as scorpions, snakes, and spiders are important producers of a myriad of peptides with different biological activities. In this review, we report the main venom-derived peptide families produced from South American organisms and their corresponding activities and biological targets. | es_ES |
| dc.description.sponsorship | Cesar de la Fuente-Nunez holds a Presidential Professorship at the University of Pennsylvania and acknowledges funding from the Procter & Gamble Company, United Therapeutics, a BBRF Young Investigator Grant, the Nemirovsky Prize, Penn Health-Tech Accelerator Award, and the Dean’s Innovation Fund from the Perelman School of Medicine at the University of Pennsylvania. Research reported in this publication was supported by the Langer Prize (AIChE Foundation), the National Institute of General Medical Sciences of the National Institutes of Health under award number R35GM138201 and the Defense Threat Reduction Agency (DTRA; HDTRA11810041 and HDTRA1-21-1-0014). The figure shown in the manuscript was prepared in BioRender.com. We thank Xunta de Galicia for a pre-doctoral fellowship 2019 co-funded with the social European funding (FSE) of the European Union (ED481A-2019/081) | es_ES |
| dc.description.sponsorship | Estados Unidos. National Institute of General Medical Sciences; R35GM138201 | es_ES |
| dc.description.sponsorship | Estados Unidos. Defense Threat Reduction Agency; HDTRA11810041 | es_ES |
| dc.description.sponsorship | Estados Unidos. Defense Threat Reduction Agency; HDTRA1-21-1-0014 | es_ES |
| dc.description.sponsorship | Xunta de Galicia; ED481A-2019/081 | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | MDPI | es_ES |
| dc.relation.uri | https://doi.org/10.3390/ijms232315437 | es_ES |
| dc.rights | Atribución 4.0 Internacional | es_ES |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
| dc.subject | Antimicrobial peptides | es_ES |
| dc.subject | Venom | es_ES |
| dc.subject | Cancer | es_ES |
| dc.subject | South America | es_ES |
| dc.subject | Neurotoxins | es_ES |
| dc.title | Biologically Active Peptides from Venoms: Applications in Antibiotic Resistance, Cancer, and Beyond [Review] | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
| UDC.journalTitle | International Journal of Molecular Sciences | es_ES |
| UDC.volume | 23 | es_ES |
| UDC.issue | 23 | es_ES |
| UDC.startPage | 15437 | es_ES |
| dc.identifier.doi | 10.3390/ijms232315437 |
