Effectiveness of rotavirus vaccination in Spain

Martinon-Torres, Federico; Bouzón Alejandro, Marta; Redondo Collazo, Lorenzo; Sánchez-Lastres, J.; Pértega-Díaz, Sonia; Seoane-Pillado, Teresa; Mantiñón Sánchez, José María

Title

Author(s)

Martinon-Torres, Federico

Bouzón Alejandro, Marta

Redondo Collazo, Lorenzo

Sánchez-Lastres, J.

Pértega-Díaz, Sonia

Seoane-Pillado, Teresa

Mantiñón Sánchez, José María

Date

2011-07-01

Citation

Martinón-Torres F, Bouzón Alejandro M, Redondo Collazo L, Sánchez Lastres JM, Pértega Díaz S, Seoane Pillado MT, Martinón Sánchez JM; ROTACOST research team. Effectiveness of rotavirus vaccination in Spain. Hum Vaccin. 2011 Jul;7(7):757-61. doi: 10.4161/hv.7.7.15576. Epub 2011 Jul 1. PMID: 21521947.

Abstract

[Abstract] With the aim of determining rotavirus vaccine effectiveness (RVVE) in Spain, from Oct-2008/Jun-2009, 467 consecutive children below 2 years old with acute gastroenteritis (AGE) were recruited using a pediatric research network (ReGALIP-www.regalip.org) that includes primary, emergency and hospital care settings. Of 467 enrolled children, 32.3% were rotavirus positive and 35.0% had received at least one dose of any rotavirus vaccine. RRVE to prevent any episode of rotavirus AGE was 91.5% (95% CI: 83.7%-95.6%). RVVE to prevent hospitalization by rotavirus AGE was 95.6% (85.6-98.6%). No differences in RVVE were found regarding the vaccine used. Rotavirus vaccines have showed an outstanding effectiveness in Spain.