Listar GI-GIGG - Artigos por autor "Laffon, Blanca"

Mostrando ítems 1-9 de 9

    • Effects of degree of urbanization and lifetime longest-held occupation on cognitive impairment prevalence in an older spanish population 

      Lorenzo-López, Laura; Millán-Calenti, José Carlos; López-López, Rocío; Diego-Díez, Clara; Laffon, Blanca; Pásaro, Eduardo; Valdiglesias, Vanessa; Maseda, Ana (Frontiers, 2017-02-13)
      [Abstract] Our aim was to estimate the prevalence of cognitive impairment in rural and urban elderly populations and to examine the relationship between lifetime occupation and general cognitive performance. A cross-sectional ...

    • Exploring genetic outcomes as frailty biomakers 

      Valdiglesias, Vanessa; Sánchez-Flores, María; Marcos-Pérez, Diego; Lorenzo-López, Laura; Maseda, Ana; Millán-Calenti, José Carlos; Pásaro, Eduardo; Laffon, Blanca (Oxford, 2018-04-19)
      [Abstract] Frailty has emerged as a reliable measure of the aging process. Because the early detection of frailty is crucial to prevent or even revert it, the use of biomarkers would allow an earlier and more objective ...

    • Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways 

      Marcos Pérez, Diego; Sánchez-Flores, María; Maseda, Ana; Lorenzo-López, Laura; Millán-Calenti, José Carlos; Strasser, Barbara; Gostner, Johanna; Fuchs, Dietmar; Pásaro, Eduardo; Valdiglesias, Vanessa; Laffon, Blanca (Elsevier para AMDA (The Society for Post-Acute and Long-Term Cara Medicine), 2017-08-08)

    • Immune biomarkers in older adults: role of physical activity 

      Valdiglesias, Vanessa; Sánchez-Flores, María; Maseda, Ana; Lorenzo-López, Laura; Marcos Pérez, Diego; López-Cortón-Facal, Ana; Strasser, Barbara; Fuchs, Dietmar; Laffon, Blanca; Millán-Calenti, José Carlos; Pásaro, Eduardo (Taylor & Francis, 2017-05-19)
      [Abstract] Aging is associated with a decline in the normal functioning of the immune system. Several studies described the relationship between immunological alterations, including immunosenescence and inflammation, and ...

    • Is salivary chromogranin A a valid psychological stress biomarker during sensory stimulation in people with advanced dementia? 

      Valdiglesias, Vanessa; Maseda, Ana; Lorenzo-López, Laura; Pásaro, Eduardo; Millán-Calenti, José Carlos; Laffon, Blanca (IOS Press, 2016-12-20)
      [Abstract] Salivary chromogranin A (sCgA) is gaining attention as a biomarker of psychological stress. The objective of this work was to determine whether individualized music intervention and multisensory stimulation ...

    • Lymphocyte subsets in a population of nonfrail elderly individuals 

      Valdiglesias, Vanessa; Sánchez-Flores, María; Maseda, Ana; Marcos Pérez, Diego; Millán-Calenti, José Carlos; Pásaro, Eduardo; Lorenzo-López, Laura; Laffon, Blanca (Taylor & Francis, 2015-07-13)
      [Abstract] Age-related frailty is characterized by increased vulnerability to stress due to decline in homeostatic reserve, which results in increased risk of adverse health outcomes including disability, hospitalization, ...

    • Serum cortisol but not oxidative stress biomarkers are related to frailty: results of a cross-sectional study in Spanish older adults 

      Marcos-Pérez, Diego; Sánchez-Flores, María; Maseda, Ana; Lorenzo-López, Laura; Millán-Calenti, José Carlos; Pásaro, Eduardo; Laffon, Blanca; Valdiglesias, Vanessa (Taylor&Francis, 2019-08-13)
      [Abstract] Frailty is a multidimensional geriatric syndrome of loss of reserves and increased vulnerability to negative health outcomes. Cortisol, the major hormone of the hypothalamic pituitary adrenal (HPA) axis, and ...

    • Suitability of Salivary Leucocytes to Assess DNA Repair Ability in Human Biomonitoring Studies by the Challenge-Comet Assay 

      Fernández-Bertólez, Natalia; Lema Arranz, Carlota; Fraga, S.; Teixeira, Joao; Pasaro, Eduardo; Lorenzo-López, Laura; Valdiglesias, Vanessa; Laffon, Blanca (Elsevier, 2022)
      [Abstract] The challenge-comet assay is a simple but effective approach that provides a quantitative and functional determination of DNA repair ability, and allows to monitor the kinetics of repair process. Peripheral blood ...

    • Toxoplasma gondii IgG serointensity is positively associated with frailty 

      Mohyuddin, Hira; Laffon, Blanca; Teixeira, Joao P.; Costa, Solange; Teixeira-Gomes, Armanda; Pásaro, Eduardo; Constantine, Niel; Dagdag, Aline; Ortmeyer, Heidi K.; Tizenberg, Boris; Afram, Liubov; Yen, Poyu; Marano, Christopher; Lowry, Christopher A.; Hoisington, Andrew J.; RachBeisel, Jill A.; Valdiglesias, Vanessa; Lema-Arranz, Carlota; Fernández-Bertólez, Natalia; Maseda, Ana; Millán-Calenti, José Carlos; Kovacs, Elizabeth J.; Gostner, Johanna M.; Fuchs, Dietmar; Brenner, Lisa A.; Lorenzo-López, Laura; Postolache, Teodor T. (Oxford University Press, 2023-11-06)
      [Abstract] Background: Persistent inflammation related to aging ("inflammaging") is exacerbated by chronic infections and contributes to frailty in older adults. We hypothesized associations between Toxoplasma gondii (T. ...