ListarGrupo de Investigación en Reumatoloxía e Saúde (GIR-S) por tema "Chondrocyte"

Mostrando ítems 1-2 de 2

    • Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis 

      Trellu, Sabine; Courties, Alice; Jaisson, Stéphane; Gorisse, Laëtitia; Gillery, Philippe; Kerdine-Römer, Saadia; Vaamonde-García, Carlos; Houard, Xavier; Ekhirch, François-Paul; Sautet, Alain; Friguet, Bertrand; Jacques, Claire; Berenbaum, Francis; Sellam, Jérémie (Springer Nature, 2019-01-11)
      [Abstract] Background: Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme involved in the removal of AGE precursors, especially ...

    • Oleate prevents palmitate-induced mitochondrial dysfunction in chondrocytes 

      Vázquez-Mosquera, María E.; Fernández-Moreno, Mercedes; Cortés-Pereira, Estefanía; Relaño, Sara; Dalmao-Fernández, Andrea; Ramos-Louro, Paula; Durán Sotuela, Alejandro; Rego-Pérez, Ignacio; Blanco García, Francisco J (Frontiers, 2021-06-15)
      [Abstract] The association between obesity and osteoarthritis (OA) in joints not subjected to mechanical overload, together with the relationship between OA and metabolic syndrome, suggests that there are systemic factors ...