• Neurogranin-Like Immunoreactivity in the Zebrafish Brain During Development 

  Alba-González, Anabel; Yáñez, Julián; Anadón, Ramón; Folgueira, Mónica (Springer Nature, 2022-08-26)

  [Abstract] Neurogranin (Nrgn) is a neural protein that is enriched in the cerebral cortex and is involved in synaptic plasticity via its interaction with calmodulin. Recently we reported its expression in the brain of the ...

• Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos 

  Valdiglesias, Vanessa; Alba-González, Anabel; Fernández-Bertólez, Natalia; Touzani, Assia; Ramos-Pan, Lucía; Reis, Ana Teresa; Moreda-Piñeiro, Jorge; Yáñez, Julián; Laffon, Blanca; Folgueira, Mónica (MDPI, 2023-08-01)

  [Abstract] Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use ...

• Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs 

  Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Teixeira, Ricardo Gonçalves; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Alba-González, Anabel; Salamini-Montemurri, Martín; Pech-Puch, Dawrin; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2021-02-11)

  [Abstract] Ruthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated ...

• RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo 

  Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Carvalho, Andreia; Fernandes, Alexandra; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2018-10-19)

  [Abstract] Ruthenium(II) complexes are currently considered a viable alternative to the widely used platinum complexes as efficient anticancer agents. We herein present the synthesis and characterization of half-sandwich ...

• Severe Neurometabolic Phenotype in NPC1−/− Zebrafish With a C-Terminal Mutation 

  Quelle Regaldie, Ana; Gandoy-Fieiras, Nerea; Villamayor, Paula R.; Maceiras, Sandra; Losada, Ana; Folgueira, Mónica; Cabezas Sáinz, Pablo; Barreiro-Iglesias, Antón; Villar López, María; Quiroga-Berdeal, María Isabel; Sánchez, Laura; Sobrido, María Jesús (Frontiers, 2023-03-17)

  [Abstract] Niemann Pick disease type C (NPC) is an autosomal recessive neurodegenerative lysosomal disorder characterized by an accumulation of lipids in different organs. Clinical manifestations can start at any age and ...

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