ListarINIBIC- REUMA - Artigos por tema "Genotype"
Mostrando ítems 1-3 de 3
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Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies
(Wiley, 2013-12-10)[Abstract] Objective: To assess candidate genes for association with osteoarthritis (OA) and identify promising genetic factors and, secondarily, to assess the candidate gene approach in OA. Methods: A total of 199 ... -
Lack of replication of interactions between polymorphisms in rheumatoid arthritis susceptibility: case–control study
(BioMed Central, 2014-09-27)[Abstract] INTRODUCTION: Approximately 100 loci have been definitively associated with rheumatoid arthritis (RA) susceptibility. However, they explain only a fraction of RA heritability. Interactions between polymorphisms ... -
Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis
(BMC, 2015-09-04)[Abstract] Introduction. Interleukin-6 (IL-6) cytokine signaling is key in Rheumatoid Arthritis (RA) pathophysiology. Blocking IL-6 receptor (IL6R) has proven to be a highly effective treatment to prevent joint damage. ...