Listar INIBIC- REUMA - Artigos por autor "Thorleifsson, Gudmar"

Mostrando ítems 1-3 de 3

    • A Meta-Analysis of Genome-Wide Association Studies Identifies Novel Variants Associated with Osteoarthritis of the Hip 

      Evangelou, Evangelos; Kerkhof, Hanneke J.; Styrkarsdottir, Unnur; Ntzani, Evangelia E.; Bos, Steffan D.; Esko, Tonu; Evans, Daniel S.; Metrustry, Sarah; Panoutsopoulou, Kalliope; Ramos, Yolande F. M.; Thorleifsson, Gudmar; Tsilidis, Konstantinos K.; Arden, Nigel; Aslam, Nadim; Bellamy, Nicholas; Birrell, Fraser; Blanco García, Francisco J; Carr, Andrew; Chapman, Kay; Day-Williams, Aaaron G.; Deloukas, Panos; Doherty, Michael; Engström, Gunnar; Helgadottir, Hafdis T.; Hofman, Albert; Ingvarsson, Thorvaldur; Jonsson, Helgi; Keis, Aime; Keurentjes, J. Christiaan; Kloppenburg, Margreet; Lind, Penelope A.; McCaskie, Andrew; Martin, Nicholas G.; Milani, Lili; Montgomery, Grant W.; Nelissen, Rob G.H.H.; Nevitt, Michael C.; Nilsson, Peter M.; Ollier, William E.R.; Parimi, Neeta; Rai, Ashok; Ralston, Stuart H.; Reed, Mike R.; Riancho, José A.; Rivadeneira, Fernando; Rodríguez-Fontenla, Cristina; Southam, Lorraine; Thorsteindottir, Unnur; Tsezou, Aspasia; Wallis, Gillian A.; Wilkinson, J. Mark; González, Antonio; Lane, Nancy E.; Lohmander, L. Stefan; Loughlin, John; Metspalu, Andres; Uitterlinden, André G.; Jonsdottir, Ingileif; Stefansson, Kari; Slagboom, P. Eline; Zeggini, Eleftheria; Meulebelt, Ingrid; Ionnidis, John P.A.; Spector, Tim D.; van Meurs, Joyce B.J.; Valdes, Ana M. (BMJ, 2013-08-29)
      [Abstract] OBJECTIVES: Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies ...

    • Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies 

      Rodríguez-Fontenla, Cristina; Calaza, Manuel; Evangelou, Evangelos; Valdés, Ana M.; Arden, Nigel; Blanco García, Francisco J; Carr, Andrew; Chapman, Kay; Deloukas, Panos; Doherty, Michael; Esko, Tonu; Garcés Aletá, Carlos M.; Gómez-Reino Carnota, Juan J.; Helgadottir, Hafids; Hofman, Albert; Jonsdottir, Ingilef; Kerkhof, Henneke J.M.; Kloppenburg, Margreet; McCaskie, Andrew; Ntzani, Evangelia E.; Ollier, William E.R.; Oreiro, Natividad; Panoutsopoulo, Kalliope; Ralston, Stuart H.; Ramos, Yolande F. M.; Riancho, José A.; Rivadeneira, Fernando; Slagboom, Eline; Styrkarsdottir, Unnur; Thorsteindottir, Unnur; Thorleifsson, Gudmar; Tsezou, Aspasia; Uitterlinden, André G.; Wallis, Gillian A.; Wilkinson, J. Mark; Zhai, Yanyan; Felson, David T.; Ioannidis, John P.A.; Loughlin, John; Metspalu, Andres; Meulenbelt, Ingrid; Stefansson, Kari; van Meurs, Joyce B.; Zeggini, Eleftheria; Spector, Timothy D.; González, Antonio (Wiley, 2013-12-10)
      [Abstract] Objective: To assess candidate genes for association with osteoarthritis (OA) and identify promising genetic factors and, secondarily, to assess the candidate gene approach in OA. Methods: A total of 199 ...

    • Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect 

      Styrkarsdottir, Unnur; Stefansdottir, Lilja; Thorleifsson, Gudmar; Stefansson, Olafur A.; Saevarsdottir, Saedis; Lund, Sigrun H.; Rafnar, Thorunn; Hoshijima, Kazuyuki; Novak, Kendra; Oreiro, Natividad; Rego-Pérez, Ignacio; Hansen, Channing; Kazmers, Nikolas; Kiemeney, Lambertus A.; Blanco García, Francisco J; Barker, Tyler; Kloppenburg, Margreet; Jurynec, Michel J.; Gudbjartsson, Daniel F.; Jonsson, Helgi; Thorsteinsdottir, Unnur; Stefansson, Kari (BMJ, 2023-03-17)
      [Abstract] Objectives: Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is unclear if EHOA is genetically different from other forms of OA. Sequence variants at ten loci have been ...