Listar INIBIC- REUMA - Artigos por título

Mostrando ítems 123-142 de 182

    • OARSI Guidelines for the Non-Surgical Management of Knee, Hip, and Polyarticular Osteoarthritis 

      Bannuru, R.R.; Osani, M.C.; Vaysbrot, E.E.; Arden, Nigel; Bennell, K.; Bierma-Zeinstra, S.M.A.; Kraus, V.B.; Lohmander, L. Stefan; Abbott, J.H.; Bhandari, M.; Blanco García, Francisco J; Espinosa, R.; Haugen, Ida K.; Lin, J.; Mandl, L.A.; Moilanen, Eeva; Nakamura, N.; Synder-Mackler, L.; McAlindon, T.E. (Elsevier, 2019-11)
      [Abstract] Objective: To update and expand upon prior Osteoarthritis Research Society International (OARSI) guidelines by developing patient-focused treatment recommendations for individuals with Knee, Hip, and Polyarticular ...

    • Oleate prevents palmitate-induced mitochondrial dysfunction in chondrocytes 

      Vázquez-Mosquera, María E.; Fernández-Moreno, Mercedes; Cortés-Pereira, Estefanía; Relaño, Sara; Dalmao-Fernández, Andrea; Ramos-Louro, Paula; Durán Sotuela, Alejandro; Rego-Pérez, Ignacio; Blanco García, Francisco J (Frontiers, 2021-06-15)
      [Abstract] The association between obesity and osteoarthritis (OA) in joints not subjected to mechanical overload, together with the relationship between OA and metabolic syndrome, suggests that there are systemic factors ...

    • One-year, efficacy and safety open label study, with a single injection of a new hyaluronan for knee OA: the SOYA trial 

      Gavin, Carlos; Blanco García, Francisco J; Pablos, José L.; Caracuel, Miguel A.; Rosas, José; Gómez-Barrena, Enrique; Navarro, Francisco; Coronel, María Pilar; Gimeno, Mercedes (DovePress, 2021-07-21)
      [Abstract] Purpose. To assess the efficacy and safety of a single injection of a new formulation of hyaluronic acid (MPS-HA2%) in patients with symptomatic knee osteoarthritis after 12 months’ follow-up. Patients and ...

    • Optical Biomarkers for the Diagnosis of Osteoarthritis through Raman Spectroscopy: Radiological and Biochemical Validation Using Ex Vivo Human Cartilage Samples 

      Casal-Beiroa, Paula; Balboa-Barreiro, Vanesa; Oreiro, Natividad; Pértega-Díaz, Sonia; Blanco García, Francisco J; Magalhaes, Joana (MDPI, 2021-03-18)
      [Abstract] Osteoarthritis (OA) is the most common rheumatic disease, characterized by progressive articular cartilage degradation. Raman spectroscopy (RS) has been recently proposed as a label-free tool to detect molecular ...

    • Organ dysfunction as determined by the SOFA score is associated with prognosis in patients with acute traumatic spinal cord injury above T6 

      Esmorís, Inés; Galeiras, Rita; Montoto Marqués, Antonio; Pértega-Díaz, Sonia (Nature, 2021-08-30)
      [Abstract] Study design: This is a retrospective, observational study. Objectives: To evaluate organ dysfunction in patients with an acute traumatic spinal cord injury (ATSCI) above T6 using the Sequential Organ Failure ...

    • Osteoarthritis endotype discovery via clustering of biochemical marker data 

      Angelini, Federico; Widera, Pawel; Mobasheri, Ali; Blair, Joseph; Struglics, André; Uebelhoer, Melanie; Hentorin, Yves; Marijnissen, Anne CA; Kloppenburg, Margreet; Blanco García, Francisco J; Haugen, Ida K.; Berenbaum, Francis; Ladel, Christoph; Larkin, Jonathan; Bay-Jensen, Anne C.; Bacardit, Jaume (BMJ, 2022-04-08)
      [Abstract] Objectives: Osteoarthritis (OA) patient stratification is an important challenge to design tailored treatments and drive drug development. Biochemical markers reflecting joint tissue turnover were measured in ...

    • Ovine mesenchymal stromal cells: morphologic, phenotypic and functional characterization for osteochondral tissue engineering 

      Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Hermida Gómez, Tamara; Fernández Vázquez, Tania; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Díaz-Prado, Silvia; Blanco García, Francisco J (PLoS ONE, 2017-01-31)
      [Abstract] Introduction. Knowledge of ovine mesenchymal stromal cells (oMSCs) is currently expanding. Tissue engineering combining scaffolding with oMSCs provides promising therapies for the treatment of osteochondral ...

    • Pain assessment during eye examination for retinopathy of prematurity screening: skin conductance versus PIPP-R 

      Ávila-Álvarez, Alejandro; Pértega-Díaz, Sonia; Vázquez Gómez, Lorena; Sucasas-Alonso, Andrea; Romero Rey, Henar; Eiriz Barbeito, Dolores; Cabana Vázquez, Montserrat (John Wiley & Sons, 2020-05)
      [Abstract] Aim: To assess changes in skin conductance during retinopathy of prematurity screening and to study the correlation between the skin conductance and a validated pain scale. Methods: Prospective observational ...

    • Plasma mitochondrial DNA levels are inversely associated with HIV-RNA levels and directly with CD4 counts: potential role as a biomarker of HIV replication 

      Pernas, Berta; Rego-Pérez, Ignacio; Tabernilla, Andrés; Balboa-Barreiro, Vanesa; Relaño, Sara; Grandal, Marta; Crespo, Manuel; Mena, Álvaro; Castro-Iglesias, Ángeles; Blanco García, Francisco J; Poveda, Eva (Oxford, 2017-08-31)
      [Abstract] Objectives. To evaluate plasma mitochondrial DNA (mtDNA) levels among HIV-infected patients and its potential role as a biomarker of residual viral replication. Methods. HIV-infected patients on follow-up at a ...

    • Platelet-rich plasma in osteoarthritis treatment: review of current evidence 

      Gato Calvo, Lucía; Magalhaes, J.; Ruiz-Romero, Cristina; Blanco García, Francisco J; Burguera, Elena F. (Sage, 2019-02-19)
      [Abstract] Platelet-rich plasma (PRP) is defined as a volume of plasma with a platelet concentration higher than the average in peripheral blood. Many basic, preclinical and even clinical case studies and trials report ...

    • Potential use of the human amniotic membrane as a scaffold in human articular cartilage repair 

      Díaz-Prado, Silvia; Rendal Vázquez, María Esther; Muiños-López, Emma; Hermida Gómez, Tamara; Rodríguez-Cabarcos, Margarita; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Springer, 2010-04-13)
      [Abstract] The human amniotic membrane (HAM) is an abundant and readily obtained tissue that may be an important source of scaffold for transplanted chondrocytes in cartilage regeneration in vivo. To evaluate the potential ...

    • Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis 

      Blanco García, Francisco J; Camacho Encina, María; González-Rodríguez, Lucía; Rego-Pérez, Ignacio; Mateos, Jesús; Fernández-Puente, Patricia; Lourido Salas, Lucía María; Rocha Loureda, Beatriz; Picchi, Florencia; Silva-Díaz, María T.; Herrero, Marta; Martínez, Helena; Verges, Josep; Ruiz-Romero, Cristina; Calamia, Valentina (Sage, 2019-08-24)
      [Abstract] Background: In the present study, we explored potential protein biomarkers useful to predict the therapeutic response of knee osteoarthritis (KOA) patients treated with pharmaceutical grade Chondroitin ...

    • Predictors of intensive care unit stay in patients with acute traumatic spinal cord injury above T6 

      Esmorís, Inés; Galeiras, Rita; Ferreiro-Velasco, María Elena; Pértega-Díaz, Sonia (Elsevier, 2022-10)
      [Abstract] Objective: The objective of this study was to identify factors associated with the intensive care unit (ICU) length of stay (LOS) of patients with an acute traumatic spinal cord injury above T6. Methods: We ...

    • Prevalence of hospital PCR-confirmed COVID-19 cases in patients with chronic inflammatory and autoimmune rheumatic diseases 

      Pablos, José L.; Abasolo, Lydia; Álvaro-Gracia, José M.; Blanco García, Francisco J; Blanco, Ricardo; Castrejón, Isabel; Fernández-Fernández, David; Fernández-Gutiérrez, Benjamín; Galindo-Izquierdo, María; González-Gay, Miguel Á.; Manrique-Arija, Sara; Mena Vázquez, Natalia; Mera Varela, Antonio; Retuerto, Miriam; Seijas-López, Álvaro (BMJ, 2020-06-12)
      [Abstract] Background: The susceptibility of patients with rheumatic diseases and the risks or benefits of immunosuppressive therapies for COVID-19 are unknown. Methods: We performed a retrospective study with patients ...

    • Prevalence of Symptomatic Axial Osteoarthritis Phenotypes in Spain and Associated Socio-Demographic, Anthropometric, and Lifestyle Variables 

      Silva-Díaz, María T.; Blanco García, Francisco J; Quevedo Vila, Víctor; Seoane-Mato, Daniel; Pérez-Ruiz, Fernando; Juan-Mas, Antonio; Pego-Reigosa, José M.; Narváez, Javier; Quilis, Neus; Cortés, Raúl; Romero-Pérez, Antonio; Fábregas Canales, Dolores; Font Gayá, Teresa; Bordoy Ferrer, Carolina; Prado-Galbarro, Francisco Javier; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad-Reyes, Sagrario (Springer, 2021-11-10)
      [Abstract] Objective. Axial osteoarthritis (OA) is a common cause of back and neck pain, however, few studies have examined its prevalence. The aim was to estimate the prevalence and the characteristics of symptomatic axial ...

    • Prevalence of Systemic Lupus Erythematosus in Spain: Higher than Previously Reported in Other Countries? 

      Cortés Verdú, Raúl; Pego-Reigosa, J.; Seoane-Mato, Daniel; Morcillo Valle, Mercedes; Palma Sánchez, Deseada; Moreno Martínez, María J.; Mayor González, Marta; Atxotegi Sáez de Buruaga, Joana; Urionagüena Onaindia, Irati; Blanco Cáceres, Boris A.; Silva-Fernández, Lucía; Sivera, Francisca; Blanco García, Francisco J; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad, Sagrario (Oxford, 2020-01-30)
      [Abstract] Objectives: Prevalence of SLE varies among studies, being influenced by study design, geographical area and ethnicity. Data about the prevalence of SLE in Spain are scarce. In the EPISER2016 study, promoted by ...

    • Prevalence of Systemic Lupus Erythematosus in Spain: Higher than Previously Reported in other Countries? 

      Cortés Verdú, Raúl; Pego-Reigosa, J.; Seoane-Mato, Daniel; Morcillo Valle, Mercedes; Palma Sánchez, Deseada; Moreno Martínez, María J.; Mayor González, Marta; Atxotegi Sáez de Buruaga, Joana; Urionagüena Onaindia, Irati; Blanco Cáceres, Boris A.; Silva-Fernández, Lucía; Sivera, Francisca; Blanco García, Francisco J; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad, Sagrario (Oxford, 2020-01-30)
      [Abstract] Objectives: Prevalence of SLE varies among studies, being influenced by study design, geographical area and ethnicity. Data about the prevalence of SLE in Spain are scarce. In the EPISER2016 study, promoted by ...

    • Prevalencia de artrosis sintomática en España: estudio EPISER2016 

      Blanco García, Francisco J; Silva-Díaz, María T.; Quevedo Vila, Víctor; Seoane-Mato, Daniel; Pérez Ruiz, Fernando; Juan-Mas, Antonio; Pego-Reigosa, J.; Narváez, Javier; Quilis, Neus; Cortés, Raúl; Romero Pérez, Antonio; Fábregas Canales, Dolores; Font Gayá, Teresa; Bordoy Ferrer, Carolina; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad, Sagrario (Elsevier, 2020-04-28)
      [Resumen] Introducción. La Sociedad Española de Reumatología elaboró en el año 2000 el estudio EPISER2000 para conocer la prevalencia de la artrosis y otras enfermedades reumáticas en España. Los cambios sociodemográficos ...

    • PROCOAC (PROspective COhort of A Coruña) description: Spanish prospective cohort to study osteoarthritis 

      Oreiro, Natividad; Raga, Ana C.; Rego-Pérez, Ignacio; Pértega-Díaz, Sonia; Silva-Díaz, Maite; Freire, Mercedes; Fernández-López, Carlos; Blanco García, Francisco J (Elsevier, 2021-05-03)
      [Abstract] Introduction and objective: The use of well characterized osteoarthritis (OA) cohorts is mandatory for the study and knowledge of this disease. Currently, there is no prospective cohort in this pathology in ...

    • Profile of matrix-remodeling proteinases in osteoarthritis: impact of fibronectin 

      Pérez-García, Selene; Carrión, Mar; Gutiérrez-Cañas, Irene; Villanueva-Romero, Raúl; Castro, David; Martínez, Carmen; González-Álvaro, Isidoro; Blanco García, Francisco J; Juarranz, Yasmina; Gomariz, Rosa P. (MDPI, 2019-12-22)
      [Abstract] The extracellular matrix (ECM) is a complex and specialized three-dimensional macromolecular network, present in nearly all tissues, that also interacts with cell surface receptors on joint resident cells. Changes ...