Paramagnetic lanthanide chelates for multicontrast MRI
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http://hdl.handle.net/2183/18343
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Paramagnetic lanthanide chelates for multicontrast MRIAutor(es)
Fecha
2016-06-02Cita bibliográfica
Cakic N., Savic T., Stricker-Shaver J., Truffault V., Platas-Iglesias C., Mirkes C., et al. Paramagnetic lanthanide chelates for multicontrast MRI. Chem. Commun. 2016, 59, 9224. https://doi.org/10.1039/C6CC04011J
Resumen
[Abstract] The preparation of a paramagnetic chelator that serves as a platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or 19F MRI contrast agent is reported. Its europium(III) complex exhibits an extremely slow water exchange rate which is optimal for the use in CEST MRI. The potential of this platform was demonstrated through a series of MRI studies on tube phantoms and animals.
Palabras clave
Contrast agents
Coordination compounds
Gadolinium
Lanthanides
NMR imaging
Coordination compounds
Gadolinium
Lanthanides
NMR imaging
Versión del editor
ISSN
1364-548X