Paramagnetic lanthanide chelates for multicontrast MRI
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Paramagnetic lanthanide chelates for multicontrast MRIAuthor(s)
Date
2016-06-02Citation
Cakic N., Savic T., Stricker-Shaver J., Truffault V., Platas-Iglesias C., Mirkes C., et al. Paramagnetic lanthanide chelates for multicontrast MRI. Chem. Commun. 2016, 59, 9224. https://doi.org/10.1039/C6CC04011J
Abstract
[Abstract] The preparation of a paramagnetic chelator that serves as a platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or 19F MRI contrast agent is reported. Its europium(III) complex exhibits an extremely slow water exchange rate which is optimal for the use in CEST MRI. The potential of this platform was demonstrated through a series of MRI studies on tube phantoms and animals.
Keywords
Contrast agents
Coordination compounds
Gadolinium
Lanthanides
NMR imaging
Coordination compounds
Gadolinium
Lanthanides
NMR imaging
Editor version
ISSN
1364-548X