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Changes in hypothalamic expression of the Lin28/let-7 system and related MicroRNAs during postnatal maturation and after experimental manipulations of puberty
(Endocrine Society, 2013)
[Abstract] Lin28 and Lin28b are related RNA-binding proteins that inhibit the maturation of miRNAs of the let-7 family and participate in the control of cellular stemness and early embryonic development. Considerable ...
Circulating levels of irisin in hypopituitary and normal subjects
(PLoS ONE, 2016-07-29)
[Abstract] Context. The recently identified myokine irisin conveys some of the benefits of exercise. Hypopituitarism with adult growth hormone deficiency (HP) is a situation characterized by decreased GH secretion and an ...
Effect of weight loss after bariatric surgery on thyroid-stimulating hormone levels in euthyroid patients with morbid obesity
(MDPI, 2019-05-20)
[Abstract] Obesity is associated with several endocrine abnormalities, including thyroid dysfunction. The objective of this study was to investigate the effect of weight loss after bariatric surgery on thyroid-stimulating ...
Cost-effectiveness analysis of preoperative treatment of acromegaly with somatostatin analogue on surgical outcome
(Elsevier, 2015-08-20)
[Abstract] Context. There is no uniform standard of care for acromegaly. Due to the high costs involved, steps must be taken to ensure the cost-effective delivery of treatment.
Objective. Taking the results of an earlier ...
Evaluation of Thyroid Hormone Replacement Dosing in Morbidly Obese Hypothyroid Patients after Bariatric Surgery-Induced Weight Loss
(MDPI, 2021-08-19)
[Abstract] The most frequent endocrine disease in obese patients is hypothyroidism. To date, there are no clear data regarding what happens to the dose of levothyroxine (LT4) after bariatric surgery (BS). The objective of ...
Gonadotrophin-releasing hormone agonist-induced pituitary adenoma apoplexy and casual finding of a parathyroid carcinoma: a case report and review of literature
(Baishideng Publishing Group, 2019-10-26)
[Absatract]
BACKGROUND
Pituitary apoplexy represents one of the most serious, life threatening endocrine emergencies that requires immediate management. Gonadotropin-releasing hormone agonist (GnRHa) can induce pituitary ...
Effectiveness of lanreotide autogel 120 mg at extended dosing intervals for acromegaly
(Springer, 2020-07-28)
[Abstract]
Purpose. Recent data indicate that extended dosing intervals (EDIs) with lanreotide autogel 120 mg are effective and well-received among patients with acromegaly who have achieved biochemical control with monthly ...
Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test
(Elsevier para European Federation of Internal Medicine, 2017-06-09)
[Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ...
Central Resistance to Thyroid Hormones in Morbidly Obese Subjects is Reversed after Bariatric Surgery-Induced Weight Loss
(MDPI, 2020-01-28)
[Abstract]
Endocrine abnormalities are common in obesity, including altered thyroid function. The altered thyroid function of obesity may be due to a mild acquired resistance to the thyroid hormone. The aim of this study ...
Beneficial effects of bariatric surgery-induced by weight loss on the proteome of abdominal subcutaneous adipose tissue
(MDPI, 2020-01-13)
[Abstract] Bariatric surgery (BS) is the most effective treatment for obesity and has a positive impact on cardiometabolic risk and in the remission of type 2 diabetes. Following BS, the majority of fat mass is lost from ...