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Frailty in older adults Is associated with plasma concentrations of inflammatory mediators but not with lymphocyte subpopulations
(Frontiers, 2018-05-16)
[Abstract] Frailty denotes a multidimensional syndrome that gives rise to vulnerability to stressors and leads to an increase of the age-related decline of different physiological systems and cognitive abilities. Aging-related ...
Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways
(Elsevier para AMDA (The Society for Post-Acute and Long-Term Cara Medicine), 2017-08-08)
Relationship between DNA damage measured by the comet-assay and cognitive function
(Elsevier, 2022-10-17)
[Abstract] Recent studies exploring the relationship between DNA damage measured by the comet assay (single-cell gel electrophoresis) and cognitive function in both animal models and humans are reviewed and summarized. ...
Association of torquetenovirus viremia with physical frailty and cognitive impairment in three independent european cohorts
(Karger, 2023-01-10)
[Abstract] Introduction: Immunosenescence and inflammaging have been implicated in the pathophysiology of frailty. Torquetenovirus (TTV), a single-stranded DNA anellovirus, the major component of the human blood virome, ...
Immune biomarkers in older adults: role of physical activity
(Taylor & Francis, 2017-05-19)
[Abstract] Aging is associated with a decline in the normal functioning of the immune system. Several studies described the relationship between immunological alterations, including immunosenescence and inflammation, and ...