Buscar
Mostrando ítems 1-10 de 29
Regulation of Angiogenesis Discriminates Tissue Resident MSCs from Effective and Defective Osteogenic Environments
(MDPI, 2020-05-28)
[Abstract] Background: The biological mechanisms that contribute to atrophic long bone non-union
are poorly understood. Multipotential mesenchymal stromal cells (MSCs) are key contributors to bone
formation and are ...
NF-κB/IKK Activation by Small Extracellular Vesicles Within the SASP
(Wiley, 2021-06-29)
[Abstract] Cellular senescence plays an important role in different biological and pathological conditions. Senescent cells communicate with their microenvironment through a plethora of soluble factors, metalloproteases ...
Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage
(Elsevier, 2020-07-07)
[Abstract]
Aging is a process of cellular and tissue dysfunction characterized by different hallmarks, including cellular senescence. However, there is proof that certain features of aging and senescence can be ameliorated. ...
Mesenchymal Stromal Cells for Articular Cartilage Repair: Preclinical Studies
(AO Research Institute Davos (ARI), 2020-08-26)
[Abstract]
Rheumatic diseases such as osteoarthritis (OA) are a major social and economic burden because of the
population aging and the lack of curative solutions. An effective cell therapy may be the best treatment ...
Gene Expression Signatures of Synovial Fluid Multipotent Stromal Cells in Advanced Knee Osteoarthritis and Following Knee Joint Distraction
(Frontiers Media S.A., 2020-10-14)
[Abstract]
Osteoarthritis (OA) is the most common musculoskeletal disorder. Although joint
replacement remains the standard of care for knee OA patients, knee joint distraction
(KJD), which works by temporarily off-loading ...
Organisational and clinical approach to osteoporosis in rheumatology: OP-SER-Excellence survey and consensus
(Elsevier, 2021-05-07)
[Abstract]
Objective.
To determine and analyse the organisational approach adopted by Spanish rheumatologists to osteoporosis (OP) to define strategic priorities.
Material and method.
A group of experts designed a ...
The Experience With Health Care of Patients With Inflammatory Arthritis: A Cross-sectional Survey Using the Instrument to Evaluate the Experience of Patients With Chronic Diseases
(Wolters Kluwer, 2021-01-27)
[Abstract]
Background: Patients' experience with health care is becoming a key component for the provision of a patient-centered health care model. The aim of this study was to assess the experience with health care of ...
High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome
(MDPI, 2021-07-07)
[Abstract] Hutchinson–Gilford progeria syndrome (HGPS) is a deadly childhood disorder, which is considered a very rare disease. It is caused by an autosomal dominant mutation on the LMNA gene, and it is characterized by ...
Influence of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Vitro and their Role in Ageing
(Springer Nature, 2020-01-03)
[Abstract]
Introduction: This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced
ageing and pluripotency markers in cell cultures where they are added.
Methods: MSC-derived ...
A Comparative Study of Doppler Ultrasound Against Temporal Artery Biopsy in the Diagnosis of Giant Cell Arteritis
(Elsevier, 2020-08-13)
[Abstract] Background. Giant cell arteritis (GCA) is a vasculitis that affects medium- and large-sized arteries. Temporal artery biopsy is the gold standard for diagnosis. In view of the high demand for temporal biopsies, ...