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Mostrando ítems 11-20 de 29
Extremophilic cyanobacteria from thermo-mineral springs of spas in Atlantic environments
(Taylor & Francis, 2022-04-12)
[Abstract] The species composition of cyanobacteria assemblages was studied in six thermo-mineral springs of spas in Atlantic environments of Galicia (NW Spain). Two are considered hot (Ta ≥ 40 °C), two intermediate (Ta ...
Development of new non-viral systems for genetic modification of senescent cells
(Cell Press, 2023-03-20)
[Abstract] Senescence is a process characterized by a prolonged irreversible cell-cycle arrest. The accumulation of senescent cells in tissues is related to aging and to the development of age-related diseases. Recently, ...
Healthcare experience among patients with type 2 diabetes: A cross-sectional survey using the IEXPAC tool
(Wiley, 2021-02-15)
[Abstract] Aim: To assess the experience with health care among patients with type 2 diabetes (T2DM) and to evaluate patients' demographic variables and healthcare-related characteristics which may affect their ...
Different associations of intentional and non-intentional non-adherence behaviors with patient experience with healthcare and patient beliefs in medications: a survey of patients with chronic conditions
(Dove Press, 2020-12-14)
[Abstract] Purpose: To investigate relationships between intentional and non-intentional non-adherence behaviors and patient experience with healthcare and beliefs in medications.
Patients and methods: This is a post ...
Genome Wide CRISPR/Cas9 Screen Identifies the Coagulation Factor IX (F9) as a Regulator of Senescence
(Nature, 2022-02-19)
[Abstract] During this last decade, the development of prosenescence therapies has become an attractive strategy as cellular senescence acts as a barrier against tumour progression. In this context, CDK4/6 inhibitors induce ...
Patients' perceptions on shared decision making during prescription of subcutaneous biological drug treatments for inflammatory arthritis: the RHEU-LIFE survey
(Wiley, 2020-08-24)
[Abstract] Objectives: The aim of this study was to explore the preferences of patients with rheumatic diseases and their perceived experience regarding participation in shared decision making (SDM) when they were prescribed ...
Immortalizing mesenchymal stromal cells from aged donors while keeping their essential features
(Hindawi, 2020-06-16)
[Abstract] Human bone marrow-derived mesenchymal stromal cells (MSCs) obtained from aged patients are prone to senesce and diminish their differentiation potential, therefore limiting their usefulness for osteochondral ...
Hydrogel-based localized nonviral gene delivery in regenerative medicine approaches: an overview
(MDPI, 2020-08-10)
[Abstract]
Hydrogel-based nonviral gene delivery constitutes a powerful strategy in various
regenerative medicine scenarios, as those concerning the treatment of musculoskeletal, cardiovascular,
or neural tissues disorders ...
Versatility of induced Pluripotent Stem Cells (iPSCs) for improving the knowledge on musculoskeletal diseases
(MDPI, 2020-08-25)
[Abstract]
Induced pluripotent stem cells (iPSCs) represent an unlimited source of pluripotent cells
capable of di erentiating into any cell type of the body. Several studies have demonstrated the valuable
use of iPSCs ...
Generation and Characterization of Human Induced Pluripotent Stem Cells (iPSCs) From Hand Osteoarthritis Patient-Derived Fibroblasts
(Nature Research, 2020-03-06)
[Abstract]
Knowledge and research results about hand osteoarthritis (hOA) are limited due to the lack of samples and animal models of the disease. Here, we report the generation of two induced pluripotent stem cell ...