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Next-Generation Sequencing and Quantitative Proteomics of Hutchinson-Gilford Progeria Syndrome-Derived Cells Point to a Role of Nucleotide Metabolism in Premature Aging
(PLOS, 2018-10-31)
[Abstract] Hutchinson-Gilford progeria syndrome (HGPS) is a very rare fatal disease characterized for accelerated aging. Although the causal agent, a point mutation in LMNA gene, was identified more than a decade ago, the ...