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Controlled trial on the effect of 10 days low-frequency repetitive transcranial magnetic stimulation (rTMS) on motor signs in Parkinson´s disease
(Wiley, 2010-07-28)
[Abstract] We evaluated the effect of low-frequency rTMS
on motor signs in Parkinson’s disease (PD), under a doubleblind
placebo-controlled trial design. PD patients were randomly
assigned to received either real (n 5 ...
Differential responses of spinal motoneurons to fatigue induced by short-lasting repetitive and isometric tasks
(Elsevier, 2016-10-24)
[Abstract] Compared to isometric activities, the neural basis of fatigue induced by repetitive tasks has been scarcely studied. Recently, we showed that during short-lasting repetitive tasks at the maximal possible rate ...
The effects of waveform and current direction on the efficacy and test–retest reliability of transcranial magnetic stimulation
(Elsevier, 2018-10-06)
[Abstract] The pulse waveform and current direction of transcranial magnetic stimulation (TMS) influence its interactions with the neural substrate; however, their role in the efficacy and reliability of single- and ...
Effects of a finger tapping fatiguing task on M1-intracortical inhibition and central drive to the muscle
(Nature, 2018)
[Abstract] The central drive to the muscle reduces when muscle force wanes during sustained MVC, and this is generally considered the neurophysiological footprint of central fatigue. The question is if force loss and the ...
Motor facilitation during real-time movement imitation in Parkinson’s disease: a virtual reality study
(Elsevier, 2013-08-06)
[Abstract] Background: Impaired temporal stability and poor motor unit recruitment are key impairments in Parkinsonian motor control during a whole spectrum of rhythmic movements, from simple finger tapping to gait. Therapies ...
Figure-ground modulation in awake primate thalamus
(National Academy of Sciences, 2015)
[Abstract] Figure-ground discrimination refers to the perception of an object, the figure, against a nondescript background. Neural mechanisms of figure-ground detection have been associated with feedback interactions ...
Effects of movement imitation training in Parkinson's disease: a virtual reality pilot study
(Elsevier, 2016-05)
[Abstract] Background. Hypometria is a clinical motor sign in Parkinson's disease. Its origin likely emerges from basal ganglia dysfunction, leading to an impaired control of inhibitory intracortical motor circuits. Some ...
Endocannabinoid CB1 receptors modulate visual output from the thalamus
(Springer, 2011-07-20)
[Abstract] Rationale Endocannabinoids have emerged as a modulatory
brain system affecting different types of synapses,
broadly distributed throughout the CNS, which explain
the diverse psychophysical effects observed ...