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Ontologies in medicinal chemistry: current status and future challenges
(Bentham Science, 2013)
[Abstract] Recent years have seen a dramatic increase in the amount and availability of data in the diverse areas of medicinal chemistry, making it possible to achieve significant advances in fields such as the design, ...
Mesenchymal stem cell functionalization for enhanced therapeutic applications
(Mary Ann Liebert, 2019-02-14)
[Abstract] Culture expansion of MSCs has detrimental effects on various cell characteristics and attributes (e.g., phenotypic changes and senescence), which, in addition to inherent interdonor variability, negatively impact ...
Prevalence and correlates of cost-related medication nonadherence to immunosuppressive drugs after heart transplantation: the international multicenter cross-sectional bright study
(Wolters Kluwer, 2020)
[Abstract] Background: Cost-related medication nonadherence (CRMNA) refers to not taking medications as prescribed because of difficulties paying for them.
Objectives: The aims of this study were (1) to assess the ...
UAV Swarm Path Planning With Reinforcement Learning for Field Prospecting
(Springer, 2022-03-03)
[Abstract] There has been steady growth in the adoption of Unmanned Aerial Vehicle (UAV) swarms by operators due to their time and cost benefits. However, this kind of system faces an important problem, which is the ...
Craniopharyngioma in the elderly: a multicenter and nationwide study in Spain
(Karger, 2020-10-09)
[Abstract] Background: Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. Aim: To evaluate the clinicopathological features and therapeutic ...
Genetic biomarkers in osteoarthritis: a quick overview
(Faculty Opinions, 2021-11-10)
[Abstract] Osteoarthritis (OA) is a chronic musculoskeletal disease with a polygenic and heterogeneous nature. In addition, when clinical manifestations appear, the evolution of the disease is usually already irreversible. ...
Extremophilic cyanobacteria from thermo-mineral springs of spas in Atlantic environments
(Taylor & Francis, 2022-04-12)
[Abstract] The species composition of cyanobacteria assemblages was studied in six thermo-mineral springs of spas in Atlantic environments of Galicia (NW Spain). Two are considered hot (Ta ≥ 40 °C), two intermediate (Ta ...
Prediction of Breast Cancer Proteins Involved in Immunotherapy, Metastasis, and RNA-Binding Using Molecular Descriptors and Artifcial Neural Networks
(Springer Nature, 2020-05-22)
[Abstract]
Breast cancer (BC) is a heterogeneous disease where genomic alterations, protein expression
deregulation, signaling pathway alterations, hormone disruption, ethnicity and environmental
determinants are involved. ...
General machine learning model, review, and experimental-theoretic study of magnolol activity in enterotoxigenic induced oxidative stress
(Bentham Science, 2017)
[Abstract] This study evaluated the antioxidative effects of magnolol based on the mouse model induced by Enterotoxigenic Escherichia coli (E. coli, ETEC). All experimental mice were equally treated with ETEC suspensions ...
Risks factors of mechanical ventilation in acute traumatic cervical spinal cord injured patients
(Springer, 2017-10-23)
[Abstract] Study design: Descriptive retrospective study.
Objectives: To analyze risk factors associated with mechanical ventilation (MV) in cases of acute traumatic Cervical Spinal Cord Injury (tCSCI).
Setting: ...