Now showing items 1-5 of 5

    • A semantic interoperability approach to support integration of gene expression and clinical data in breast cancer 

      Alonso-Calvo, Raúl; Paraíso-Medina, Sergio; Pérez-Rey, David; Alonso-Oset, Enrique; Stiphout, Ruud van; Taylor, Marian; Buffa, Francesca; Fernández-Lozano, Carlos; Pazos, A.; Maojo, Víctor (Elsevier, 2017-06-05)
      [Abstract] Introduction. The introduction of omics data and advances in technologies involved in clinical treatment has led to a broad range of approaches to represent clinical information. Within this context, patient ...
    • Biomedical data integration in computational drug design and bioinformatics 

      Seoane, José A.; Aguiar-Pulido, Vanessa; Munteanu, Cristian-Robert; Rivero, Daniel; Rabuñal, Juan R.; Dorado, Julián; Pazos, A. (Bentham Science, 2013)
      [Abstract In recent years, in the post genomic era, more and more data is being generated by biological high throughput technologies, such as proteomics and transcriptomics. This omics data can be very useful, but the real ...
    • Machine learning analysis of TCGA cancer data 

      Liñares Blanco, Jose; Pazos, A.; Fernández-Lozano, Carlos (PeerJ Inc., 2021)
      [Abstract] In recent years, machine learning (ML) researchers have changed their focus towards biological problems that are difficult to analyse with standard approaches. Large initiatives such as The Cancer Genome Atlas ...
    • SNOMED2HL7: a tool to normalize and bind SNOMED CT concepts to the HL7 Reference Information Model 

      Pérez-Rey, David; Alonso-Calvo, Raúl; Paraíso-Medina, Sergio; Munteanu, Cristian-Robert; García-Remesal, Miguel (Elsevier, 2017-10)
      [Abstract] BACKGROUND: Current clinical research and practice requires interoperability among systems in a complex and highly dynamic domain. There has been a significant effort in recent years to develop integrative common ...
    • SNP locator: a candidate SNP selection tool 

      Seoane, José A.; Aguiar-Pulido, Vanessa; Cabarcos, Alba; Quintela, Sonsoles; Rabuñal, Juan R.; Dorado, Julián (Inderscience, 2013)
      [Abstract] In this work, a data integration approach using a federated model based on a service oriented architecture (SOA) is presented. The BioMOBY middleware was used to implement each service which is part of the ...