Listar GI-DICOMOSA - Artigos por data de publicación
Mostrando ítems 21-38 de 38
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Low Vitamin D Levels and Frailty Status in Older Adults: a Systematic Review and Meta-Analysis
(2020)[Abstract] Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the association between low ... -
Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y)
(2020)[Abstrac] Titanium dioxide nanoparticles (TiO2 NPs) have a wide variety of applications in many consumer products, including as food additives, increasing the concern about the possible hazards that TiO2 NPs may pose to ... -
Nuevos modelos de atención sanitaria para las personas transgénero en el sistema sanitario español: demandas, controversias y reflexiones
(2020)[Resumen] La atención sanitaria a las personas transgénero en España se ha establecido de manera progresiva desde 1999, año en que Andalucía crea la primera unidad multidisciplinar para el tratamiento integral de la ... -
Gender-Affirming Hormone Therapy Modifies the CpG Methylation Pattern of the ESR1 Gene Promoter After Six Months of Treatment in Transmen
(2020)[Abstract] Background Brain sexual differentiation is a process that results from the effects of sex steroids on the developing brain. Evidence shows that epigenetics plays a main role in the formation of enduring brain ... -
Analysis of Four Polymorphisms Located at the Promoter of the Estrogen Receptor Alpha ESR1 Gene in a Population With Gender Incongruence
(2020)[Abstract] Introduction: Gender incongruence defines a state in which individuals feel discrepancy between the sex assigned at birth and their gender. Some of these people make a social transition from male to female ... -
Minimum Information for Reporting on the Comet Assay (MIRCA): Recommendations for Describing Comet Assay Procedures and Results
(2020)[Abstract] The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental ... -
DNA Damage in Circulating Leukocytes Measured With the Comet Assay May Predict the Risk of Death
(2021)[Abstract] The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, ... -
Implications of the Estrogen Receptor Coactivators SRC1 and SRC2 in the Biological Basis of Gender Incongruence
(2021)[Abstract] Introduction Brain sexual differentiation results from the effects of sex steroids on the developing brain. The presumptive route for brain masculinization is the direct induction of gene expression via activation ... -
The hCOMET Project: International Database Comparison of Results with the Comet Assay in Human Biomonitoring. Baseline Frequency of DNA Damage and Effect of Main Confounders
(2021)[Abstract] The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification ... -
Epigenetics Is Implicated in the Basis of Gender Incongruence: An Epigenome-Wide Association Analysis
(2021)[Abstract] Introduction: The main objective was to carry out a global DNA methylation analysis in a population with gender incongruence before gender-affirming hormone treatment (GAHT), in comparison to a cisgender ... -
Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells
(2021)[Abstract] Standard toxicity tests might not be fully adequate for evaluating nanomaterials since their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block micronucleus (CBMN) ... -
“Micronuclei and Disease” special issue: Aims, scope, and synthesis of outcomes
(2021)[Abastract] The purpose of the “Micronuclei and Disease” special issue (SI) is to: (i) Determine the level of evidence for association of micronuclei (MN), a biomarker of numerical and structural chromosomal aberrations, ... -
Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Oxi-Immune Markers, Clinical Parameters and Modifiable Risk Factors
(2021)[Abstract] Ageing is accompanied with a decline in several physiological systems. Frailty is an age-related syndrome correlated to the loss of homeostasis and increased vulnerability to stressors, which is associated with ... -
Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage
(MDPI, 2021-07-27)[Abstract] Metal oxide nanoparticles (NPs) have a wide variety of applications in many consumer products and biomedical practices. As a result, human exposure to these nanomaterials is highly frequent, becoming an issue ... -
Editorial: Research in Transgender Healthcare: What Have We Learned and Where Are We Going?
(2022)[Abstract] Gender incongruence (GI) is defined as “an individual’s discontent with their assigned gender and their identification with a gender other than that associated with their birth sex based on physical sex ... -
Suitability of Salivary Leucocytes to Assess DNA Repair Ability in Human Biomonitoring Studies by the Challenge-Comet Assay
(Elsevier, 2022)[Abstract] The challenge-comet assay is a simple but effective approach that provides a quantitative and functional determination of DNA repair ability, and allows to monitor the kinetics of repair process. Peripheral blood ... -
Assessing the in Vitro Toxicity of Airborne (Nano)Particles to the Human Respiratory System: From Basic to Advanced Models [Review]
(Taylor & Francis, 2023-01-24)[Abstract] Several studies have been conducted to address the potential adverse health risks attributed to exposure to nanoscale materials. While in vivo studies are fundamental for identifying the relationship between ... -
Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos
(MDPI, 2023-08-01)[Abstract] Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use ...