Listar GI-FENM - Artigos por autor "Vázquez, María J."

Mostrando ítems 1-5 de 5

    • Central ghrelin regulates peripheral lipid metabolism in a growth hormone-independent fashion 

      Sangiao-Alvarellos, Susana; Vázquez, María J.; Varela, Luis; Nogueiras, Rubén; Saha, Asish K.; Cordido, Fernando; López, Miguel; Diéguez, Carlos (Oxford para Endocrine Society, 2009-10-01)
      [Abstract] GH plays a major role in the regulation of lipid metabolism and alterations in GH axis elicit major changes in fat distribution and mobilization. For example, in patients with GH deficiency (GHD) or in mice ...

    • Ghrelin and lipid metabolism: key partners in energy balance 

      Varela, Luis; Vázquez, María J.; Cordido, Fernando; Nogueiras, Rubén; Vidal-Puig, Antonio; Diéguez, Carlos; López, Miguel (Bioscientifica para Society for Endocrinoloogy, 2011-04-01)
      [Abstract] Ghrelin, the endogenous ligand of the GH secretagogue receptor, has a pleiotropic role in the modulation of energy balance. Recent evidence has demonstrated that besides its orexigenic role, ghrelin regulates ...

    • Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism 

      Sangiao-Alvarellos, Susana; Helming, Steffen; Vázquez, María J.; Klussmann, Sven; Cordido, Fernando (Elsevier, 2011)
      [Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ...

    • Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3 

      Heras, Violeta; Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Sánchez-Tapia, María J.; Ruiz-Pino, Francisco; Roa, Juan; Lara-Chica, Maribel; Morrugares-Carmona, Rosario; Jouy, Nathalie; Abreu, Ana P.; Prevot, Vincent; Belsham, Denise; Vázquez, María J.; Calzado, Marco A.; Pinilla, Leonor; Gaytán, Francisco; Latronico, Ana C.; Kaiser, Ursula B.; Castellano, Juan M.; Tena-Sempere, Manuel (Public Library of Science (PLoS), 2019-11-07)
      [Abstract] Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; ...

    • Influence of ghrelin and growth hormone deficiency on AMP-activated protein kinase and hypothalamic lipid metabolism 

      Sangiao-Alvarellos, Susana; Varela, Luis; Vázquez, María J.; Boit, K. Da; Saha, A.K.; Cordido, Fernando; Diéguez, Carlos; López, Miguel (Wiley, 2010-03-08)
      [Abstract] Current evidence demonstrates that the stomach-derived hormone ghrelin, a potent growth hormone (GH) secretagogue, promotes feeding through a mechanism involving the short-term activation of hypothalamic ...