• Prostate carcinoma and stem cells 

      Antón-Aparicio, Luis M.; Cassinello Espinosa, J.; García Campelo, Rosario; Gómez Veiga, Francisco; Díaz-Prado, Silvia; Aparicio Gallego, Guadalupe (Springer, 2007-02)
      [Abstract] Stem cells, as classically defined, are cells with a capacity to self-renew and to generate daughter cells that can differentiate down several cell lineages to form all of the cell types that are found in the ...
    • Recomendaciones diagnósticas y terapéuticas en el sobrepeso y la obesidad durante la adolescencia 

      Calañas-Continente, Alfonso; Arrizabalaga, Juan José; Caixás, Assumpta; Cordido, Fernando (Elsevier, 2010-07-17)
    • Relevant networks involving the p53 signalling pathway in renal cell carcinoma 

      Medina Villaamil, Vanessa; Aparicio Gallego, Guadalupe; Santamarina, Isabel; Valbuena Ruvira, L.; Valladares-Ayerbes, Manuel; Antón-Aparicio, Luis M. (Master Publishing Group, 2011)
      [Abstract] Introduction: Renal cell carcinoma is the most common type of kidney cancer. A better understanding of the critical pathways and interactions associated with alterations in renal function and renal tumour ...
    • Respuesta secretora de PYY1-36 y PYY3-36 en sujetos normales tras la ingesta de una comida mixta 

      Penín Álvarez, Manuel; Pérez-Fontán, Miguel; García-Buela, Jesús; Isidro, María Luisa; Martínez, Teresa; Outeiriño-Blanco, Elena; Rodríguez Carmona, Ana; Sangiao-Alvarellos, Susana; Vidal, Ovidio; Cordido, Fernando (Elsevier para Sociedad Española de Endocrinología y Nutrición, 2008-12-25)
      [Resumen] Introducción. El péptido YY (PYY) tiene 36 aminoácidos y lo sintetizan fundamentalmente las células L del intestino. El PYY aumenta tras las comidas y alcanza su nadir tras el ayuno. Tras la ingestión se liberan ...
    • Role of neurokinin B in the control of female puberty and Its modulation by metabolic status 

      Navarro, Víctor M.; Ruiz-Pino, Francisco; Sánchez-Garrido, Miguel A.; García-Galiano, David; Hobbs, Samuel J.; Manfredi-Lozano, María; León, Silvia; Sangiao-Alvarellos, Susana; Castellano, Juan M.; Clifton, Donald K.; Pinilla, Leonor; Steiner, Robert A.; Tena-Sempere, Manuel (Society of Neuroscience, 2012-02-15)
      [Abstract] Human genetic studies have revealed that neurokinin B (NKB) and its receptor, neurokinin-3 receptor (NK3R), are essential elements for normal reproduction; however, the precise role of NKB–NK3R signaling in the ...
    • Role of taxanes in advanced prostate cancer 

      Cassinello Espinosa, J.; Carballido Rodríguez, J.; Antón-Aparicio, Luis M. (Springer, 2016-02-08)
      [Abstract] Advanced prostate cancer is an androgen-dependent disease for which the initial treatment is an androgen deprivation maneuver. However, some primary resistances to hormonal treatment occur with increasing incidence ...
    • Searching for Hif1-α interacting proteins in renal cell carcinoma 

      Medina Villaamil, Vanessa; Aparicio Gallego, Guadalupe; Santamarina, Isabel; Valladares-Ayerbes, Manuel; Antón-Aparicio, Luis M. (Springer para Federation of Spanish Oncology Sociesties (FESEO), 2012-08-28)
      [Abstract] Introduction. Kidney tumours are frequently characterised by hypoxic conditions due to a local imbalance between oxygen (O2) supply and consumption. Hif1-α regulates angiogenesis, tumour growth, tumour progression, ...
    • Serum levels of anti-alphaGalactosyl antibodies predict survival and peritoneal dialysis-related enteric peritonitis rates in patients undergoing renal replacement therapy 

      Pérez-Fontán, Miguel; Máñez, Rafael; Rodríguez-Carmona, Ana; Peteiro, Javier; Martínez, Verónica; García Falcón, María Teresa; Doménech, Nieves (Elsevier, 2006-11-06)
      [Abstract] Background: Anti-Galα1-3Gal antibodies (anti-αGal) represent a significant fraction of natural antibodies and were implicated in several disease states, yet their origin and physiological significance remain ...
    • Serum levels of the adipomyokine irisin in patients with chronic kidney disease 

      Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel; Sangiao-Alvarellos, Susana; García Falcón, María Teresa; Pena-Bello, Lara; López-Muñiz, Andrés; Cordido, Fernando (Elsevier, 2016-12-14)
      [Abstract] Background. Irisin is an adipomyokine with claimed anti-obesity and anti-diabetic effects. This hormone has been insufficiently studied in patients with advanced chronic kidney disease (CKD). Objective. To ...
    • Sexual dimorphism on growth hormone secretion after oral glucose administration 

      Outeiriño-Blanco, Elena; García-Buela, Jesús; Sangiao-Alvarellos, Susana; Brandón-Sandá, Iria; Pena-Bello, Lara; Pértega-Díaz, Sonia; Martínez, T.; Cordido, Fernando (Thieme, 2012-02-16)
      [Abstract] Sexual dimorphism of GH secretion is unclear in humans. There is evidence that oral glucose (OG) administration initially decreases and subsequently stimulates GH secretion. Our aim was to study fasting GH ...
    • Short-term regulation of peptide YY secretion by a mixed meal or peritoneal glucose-based dialysate in patients with chronic renal failure 

      Pérez-Fontán, Miguel; Cordido, Fernando; Rodríguez Carmona, Ana; Penín Álvarez, Manuel; Díaz-Cambre, Helena; López-Muñiz, Andrés; Sangiao-Alvarellos, Susana; García-Buela, Jesús (Oxford, 2008-05-23)
    • State of the art in silico tools for the study of signaling pathways in cancer 

      Medina Villaamil, Vanessa; Aparicio Gallego, Guadalupe; Santamarina, Isabel; Valladares-Ayerbes, Manuel; Antón-Aparicio, Luis M. (MDPI, 2012-05-29)
      [Abstract] In the last several years, researchers have exhibited an intense interest in the evolutionarily conserved signaling pathways that have crucial roles during embryonic development. Interestingly, the malfunctioning ...
    • Status of SARS-CoV-2 infection in patients on renal replacement therapy. Report of the COVID-19 Registry of the Spanish Society of Nephrology (SEN) 

      Sánchez-Álvarez, Emilio; Pérez-Fontán, Miguel; Jiménez Martín, Carlos; Blasco Pelícano, Miquel; Cabezas Reina, Carlos Jesús; Sevillano Prieto, Ángel M.; Melilli, Edoardo; Crespo Barrios, Marta; Macía Heras, Manuel; Pino y Pino, María Dolores del (Elsevier, 2020-05-01)
      [Abstract] Introduction: The recent appearance of the SARS-CoV-2 coronavirus pandemic has had a significant impact on the general population. Patients on renal replacement therapy (RRT) have not been unaware of this ...
    • Testicular expression of the Lin28/let-7 system: hormonal regulation and changes during postnatal maturation and after manipulations of puberty 

      Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Ruiz-Pino, Francisco; León, Silvia; Morales, Concepción; Cordido, Fernando; Gaytán, Francisco; Pinilla, Leonor; Tena-Sempere, Manuel (Nature, 2015-10-23)
      [Abstract] The Lin28/let-7 system, which includes the RNA-binding proteins, Lin28a/Lin28b, and let-7 miRNAs, has emerged as putative regulator of puberty and male gametogenesis; yet, its expression pattern and regulation ...
    • The decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors 

      Cordido, Fernando; García-Buela, Jesús; Sangiao-Alvarellos, Susana; Martínez, Teresa; Vidal, Ovidio (Hindawi, 2010)
      [Abstract] The aim of the present study was to evaluate the relationship between GHRH-induced GH secretion in obese premenopausal women and cardiovascular risk markers or insulin resistance. Premenopausal obese women, aged ...
    • The modality of dialysis does not influence atheromatous vascular disease progression or cardiovascular outcomes in dialysis patients without previous cardiovascular disease 

      Borrás Sans, Mercé; Pérez-Fontán, Miguel; Martínez-Alonso, Monserrat; Bajo, Auxiliadora; Betriu, Angels; Valdivielso, José Manuel; Fernández, Elvira (PLOS, 2017-11-02)
      [Abstract] Background. There is limited and inconclusive information regarding the influence of the modality of renal replacement therapy on the atherosclerotic burden of patients on dialysis. The aim of this study was to ...
    • Thyroid Function Alteration in Obesity and the Effect of Bariatric Surgery 

      Cordido, María; Juiz-Valiña, Paula; Urones Cuesta, Paula; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2022-02-28)
      [Abstract] The most common endocrine disease in obesity is hypothyroidism and secondary endocrine alterations, including abnormal thyroid function, are frequent in obesity. It is unclear whether impaired thyroid function ...
    • Tissue effects of glutamine in rectal cancer patients treated with preoperative chemoradiotherapy 

      Vidal-Casariego, Alfonso; Hernando-Martín, Mercedes; Calleja-Fernández, Alicia; Cano-Rodríguez, Isidoro; Cordido, Fernando; Ballesteros-Pomar, María D. (SENPE (Sociedad Española de Nutrición Parentelar y Entelar), 2015)
      [Abstract] Background: The aim was to evaluate the effects of glutamine on tumor regression and histological damage in patients with rectal patients following chemoradiotherapy previous to surgery. Material and methods: ...
    • Tratamiento quirúrgico de la obesidad: recomendaciones prácticas basadas en la evidencia 

      Morales, M. José; Díaz-Fernández, María Jesús; Caixás, Assumpta; Goday, Albert; Moreiro, José; Arrizabalaga, Juan José; Calañas-Continente, Alfonso; Cuatrecasas, Guillem; García Luna, Pedro Pablo; Masmiquel, Lluís; Monereo, Susana; Moreno, Basilio; Ricart, Wilfred; Vidal, Josep; Cordido, Fernando (Elsevier, 2008)
      [Resumen] La obesidad mórbida es, habitualmente, refractaria a los tratamientos convencionales, por lo que la modificación de hábitos dietéticos y de actividad física y/o el uso de fármacos consiguen pérdidas de peso ...
    • Treatment of sunitinib-induced hypertension in solid tumor by nitric oxide donors 

      León-Mateos, L.; Mosquera, J.; Antón-Aparicio, Luis M. (Elsevier, 2015-09-10)
      [Abstract] Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) are overexpressed in the majority of renal cell carcinomas. This characteristic has supported the rationale of targeting VEGF-driven tumour ...