ListarGI-TCMR - Artigos por tema "Mitochondria"

Mostrando ítems 1-4 de 4

    • FASN activity is important for the initial stages of the induction of senescence 

      Fafián Labora, Juan Antonio; Carpintero-Fernández, Paula; Jordan, Samuel James Davison; Shikh-Bahaei, Tamanna; Abdullah, Sana Mohammad; Mahenthiran, Midusa; Rodríguez-Navarro, José Antonio; Niklison-Chirou, María Victoria; O’Loghlen, Ana (Springer Nature, 2019-04-08)
      [Abstract] Senescent cells accumulate in several tissues during ageing and contribute to several pathological processes such as ageing and cancer. Senescence induction is a complex process not well defined yet and is ...

    • Hydrogen sulfide and inflammatory joint diseases 

      Burguera, Elena F.; Meijide-Faílde, Rosa; Blanco García, Francisco J (Bentham, 2017)
      [Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with ...

    • Mitochondrial activity is modulated by TNFα and IL-1β in normal human chondrocyte cells 

      López-Armada, María José; Caramés, Beatriz; Martín, M.A.; Cillero-Pastor, B.; Lires-Dean, M.; Fuentes Boquete, Isaac Manuel; Arenas, J.; Blanco García, Francisco J (Elsevier, 2006-05-05)
      [Abstract] Objective. Pro-inflammatory cytokines play an important role in osteoarthritis (OA). In osteoarthritic cartilage, chondrocytes exhibit an alteration in mitochondrial activity. This study analyzes the effect of ...

    • The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint 

      Vaamonde-García, Carlos; Loureiro, Jesús; Valcárcel Ares, Marta Noa; Riveiro Naveira, Romina R.; Ramil-Gómez, Olalla; Hermida-Carballo, Laura; Centeno, Alberto; Meijide-Faílde, Rosa; Blanco García, Francisco J; López-Armada, María José (BioMed Central, 2017-06-12)
      [Abstract] Background. Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether ...