ListarGI-TCMR - Artigos por tema "Gene therapy"

Mostrando ítems 1-4 de 4

    • Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy 

      Álvarez-Rivera, Fernando; Rey-Rico, Ana; Venkatesan, Jagadeesh K.; Díaz-Gómez, Luis; Cucchiarini, Magali; Concheiro, Ángel; Álvarez-Lorenzo, Carmen (MDPI, 2020-04-09)
      [Abstract] As an alternative to eye drops and ocular injections for gene therapy, the aim of this work was to design for the first time hydrogel contact lenses that can act as platforms for the controlled delivery of ...

    • Current trends in viral gene therapy for human orthopaedic regenerative medicine 

      Venkatesan, Jagadeesh Kumar; Rey-Rico, Ana; Cucchiarini, Magali (Springer, 2019-02-21)
      [Abstract] Background: Viral vector-based therapeutic gene therapy is a potent strategy to enhance the intrinsic reparative abilities of human orthopaedic tissues. However, clinical application of viral gene transfer remains ...

    • Hydrogel-based localized nonviral gene delivery in regenerative medicine approaches: an overview 

      Carballo-Pedrares, Natalia; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia; Rey-Rico, Ana (MDPI, 2020-08-10)
      [Abstract] Hydrogel-based nonviral gene delivery constitutes a powerful strategy in various regenerative medicine scenarios, as those concerning the treatment of musculoskeletal, cardiovascular, or neural tissues disorders ...

    • Scaffold-Mediated Gene Delivery for Osteochondral Repair 

      Madry, Henning; Venkatesan, Jagadeesh Kumar; Carballo-Pedrares, Natalia; Rey-Rico, Ana; Cucchiarini, Magali (MDPI, 2020-09-29)
      [Abstract] Osteochondral defects involve both the articular cartilage and the underlying subchondral bone. If left untreated, they may lead to osteoarthritis. Advanced biomaterial-guided delivery of gene vectors has ...