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Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer
(MDPI, 2012-04-05)
[Abstract] We aim to estimate the diagnostic performances of anterior gradient homolog-2 (AGR2) and Leucine-rich repeat-containing-G-protein-coupled receptor 5 (LGR5) in peripheral blood (PB) as mRNA biomarkers in colorectal ...
Evaluation of COX-2, EGFR, and p53 as biomarkers of non-dysplastic oral leukoplakias
(Elsevier, 2010-07-01)
[Abstract] Objective. Identify candidate SEBs (surrogate endpoint biomarkers) for premalignant trends in head and neck mucosa.
Study design. Study, by qPCR (quantitative real-time polymerase chain reaction), the expression ...
Evaluation of Plakophilin-3 mRNA as a biomarker for detection of circulating tumor cells in gastrointestinal cancer patients
(American Association for Cancer Research, 2010-05-25)
[Abstract] Background: This study aims to assess Plakophilin-3 (PKP3) as a surrogate biomarker of circulating tumor cells in patients with gastrointestinal cancer.
Methods: The primary aim is to estimate the diagnostic ...
Bone marrow cells immunomagnetically selected for CD271+ antigen promote in vitro the repair of articular cartilage defects
(Mary Ann Liebert, 2011-03-22)
[Abstract] Objective: The purposes of this project were to quantify the cells expressing the mesenchymal stem cell (MSC) marker CD271 in synovial membranes from human osteoarthritic (OA) and healthy joints, and to determine ...
Intraarticular administration effect of hydrogen sulfide on an in vivo rat model of osteoarthritis
(MDPI, 2020-10-08)
[Abstract]
Osteoarthritis (OA) is the most common articular chronic disease. However, its current treatment is limited and mostly symptomatic. Hydrogen sulfide (H2S) is an endogenous gas with recognized physiological ...
Is myofascial release therapy cost-effective when compared with manual therapy to treat workers’ mechanical neck pains?
(Elsevier, 2020-09-12)
[Abstract]
Objective: The aim of this study was to do a cost-benefit analysis of myofascial release therapy (MRT) compared to
manual therapy (MT) for treating occupational mechanical neck pain.
Methods: Variables regarding ...
Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their tole in ageing
(Springer Nature, 2020-01-03)
[Abstract]
Introduction: This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced
ageing and pluripotency markers in cell cultures where they are added.
Methods: MSC-derived ...
Medicina termal en enfermedades reumáticas: evidencia científica y actualidad de los mecanismos de acción
(Sociedad Española de Hidrología Médica, 2020)
[Resumen] La patología músculo-esquelética es la responsable en la actualidad de la mayoría de las prescripciones de la curas termales en diversos países. La eficacia de la balneoterapia en reumatología, ha sido confirmada ...
Mesenchymal stromal cells for articular cartilage repair: preclinical studies
(AO Research Institute Davos (ARI), 2020-08-26)
[Abstract]
Rheumatic diseases such as osteoarthritis (OA) are a major social and economic burden because of the
population aging and the lack of curative solutions. An effective cell therapy may be the best treatment ...
Therapeutic characteristics of Galician mineral and thermal waters (NW-Spain) ascribed to their local/regional geological setting
(Springer, 2017-03-06)
[Abstract]
Galicia is located in the NW corner of the Iberian Peninsula (Spain). From a geological point of view, the
territory belongs to the Hercynian chain and, more specifically, to a large outcrop dominated by igneous ...