Listar por autor "Rodríguez-Navarro, José Antonio"

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    • Extracellular Vesicles as Potential Tools for Regenerative Therapy 

      Rodríguez-Navarro, José Antonio; Pascual-Guerra, Jorge; Sacristán, Silvia; Nogales, Maria del Carmen; Fafián Labora, Juan Antonio (Taylor & Francis Online, 2020-09-08)
      [Abstract] Small extracellular vesicles released by fibroblasts from young human donors diminish lipid peroxidation in senescent cells and in different old mice organs due to their enrichment in Glutathione-S-transferase Mu ...

    • FASN activity is important for the initial stages of the induction of senescence 

      Fafián Labora, Juan Antonio; Carpintero-Fernández, Paula; Jordan, Samuel James Davison; Shikh-Bahaei, Tamanna; Abdullah, Sana Mohammad; Mahenthiran, Midusa; Rodríguez-Navarro, José Antonio; Niklison-Chirou, María Victoria; O’Loghlen, Ana (Springer Nature, 2019-04-08)
      [Abstract] Senescent cells accumulate in several tissues during ageing and contribute to several pathological processes such as ageing and cancer. Senescence induction is a complex process not well defined yet and is ...

    • Small extracellular vesicles have GST activity and ameliorate senescence-related tissue damage 

      Fafián Labora, Juan Antonio; Rodríguez-Navarro, José Antonio; O’Loghlen, Ana (Elsevier, 2020-07-07)
      [Abstract] Aging is a process of cellular and tissue dysfunction characterized by different hallmarks, including cellular senescence. However, there is proof that certain features of aging and senescence can be ameliorated. ...