Listar por autor "Martínez-Nava, Gabriela Angélica"

Mostrando ítems 1-3 de 3

    • Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress 

      Medina-Luna, Daniel; Santamaría-Olmedo, Mónica Guadalupe; Zamudio-Cuevas, Yessica; Martínez-Flores, Karina; Fernández-Torres, Javier; Martínez-Nava, Gabriela Angélica; Clavijo-Cornejo, Denise; Hernández-Díaz, Cristina; Olivos-Meza, Anell; Gómez-Quiroz, Luis Enrique; Gutiérrez-Ruiz, María Concepción; Pineda, Carlos; Blanco García, Francisco J; Reginato, Anthony M.; López-Reyes, Alberto (BMC, 2017-06-12)
      [Abstract] Background, Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation. The aim of this ...

    • mtDNA Haplogroup A Enhances the Effect of Obesity on the Risk of Knee OA in a Mexican Population 

      Ramos-Louro, Paula; Arellano Pérez Vertti, Rubén Daniel; López Reyes, Alberto; Martínez-Nava, Gabriela Angélica; Espinosa, Rolando; Pineda, Carlos; González-Galarza, Faviel Francisco; Argüello Astorga, Rafael; Aguilar Muñiz, Lizette Sarai; Hernández Terán, Fernando; Parra Torres, Nancy Marbella; Durán Sotuela, Alejandro; Fernández-Moreno, Mercedes; Balboa-Barreiro, Vanesa; Blanco García, Francisco J; Rego-Pérez, Ignacio (Nature, 2022-03-25)
      [Abstract] To evaluate the influence of mitochondrial DNA haplogroups on the risk of knee OA in terms of their interaction with obesity, in a population from Mexico. Samples were obtained from (n = 353) knee OA patients ...

    • Soluble inflammatory mediators of synoviocytes stimulated by monosodium urate crystals induce the production of oxidative stress, pain, and inflammation mediators in chondrocytes 

      López-Reyes, Alberto; Medina-Luna, Daniel; Santamaría-Olmedo, Mónica; Martínez-Flores, Karina; Zamudio-Cuevas, Yessica; Fernández-Torres, Javier; Martínez-Nava, Gabriela Angélica; Olivos-Meza, Anell; Camacho-Rea, Carmen; Fernández-Moreno, Mercedes; Blanco García, Francisco J; Pineda, Carlos (Springer, 2021-03-16)
      [Abstract] We hypothesized that the secretion of inflammatory mediators from synoviocytes affects the chondrocyte homeostasis of articular cartilage. This study was a preliminary attempt to elucidate the molecular mechanisms ...