Listar por autor "Lechuga-Vieco, Ana Victoria"
Mostrando ítems 1-2 de 2
-
Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis
Scotece, Morena; Rego-Pérez, Ignacio; Lechuga-Vieco, Ana Victoria; Centeno, Alberto; Jiménez-Gómez, María Concepción; Filgueira-Fernández, P.; Vaamonde-García, Carlos; Enríquez, José Antonio; Blanco García, Francisco J (Nature, 2021-04-27)[Abstract] It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced ... -
mtDNA variability determines spontaneous joint aging damage in a conplastic mouse model
Scotece, Morena; Vaamonde-García, Carlos; Lechuga-Vieco, Ana Victoria; Centeno Cortés, Alberto; Jiménez Gómez, María Concepción; Filgueira-Fernández, Purificación; Rego-Pérez, Ignacio; Enríquez, José Antonio; Blanco García, Francisco J (Impact Journals, 2022-07-02)[Abstract] Mitochondria and mtDNA variations contribute to specific aspects of the aging process. Here, we aimed to investigate the influence of mtDNA variation on joint damage in a model of aging using conplastic mice. A ...