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Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis
(Multidisciplinary Digital Publishing Institute, 2016)
Okadaic acid (OA) and dinophysistoxins (DTXs) are the main toxins responsible for diarrhetic shellfish poisoning (DSP) intoxications during harmful algal blooms (HABs). Although the genotoxic and cytotoxic responses to OA ...
Okadaic Acid: More than a Diarrheic Toxin
(Multidisciplinary Digital Publishing Institute, 2013)
Okadaic acid (OA) is one of the most frequent and worldwide distributed marine toxins. It is easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be consumed by humans causing alimentary ...
Applicability of EU(7)-PIM criteria in cross-national studies in European countries
(2019)
[Abstract] Background: The European Union (EU)(7)-PIM (potentially inappropriate medication) list
presents the most comprehensive and up-to-date tool for evaluation of PIM prescribing in
Europe; however, several ...
Okadaic Acid Meet and Greet: An Insight into Detection Methods, Response Strategies and Genotoxic Effects in Marine Invertebrates
(Multidisciplinary Digital Publishing Institute, 2013)
Harmful Algal Blooms (HABs) constitute one of the most important sources of contamination in the oceans, producing high concentrations of potentially harmful biotoxins that are accumulated across the food chains. One such ...
Low Vitamin D Levels and Frailty Status in Older Adults: a Systematic Review and Meta-Analysis
(2020)
[Abstract] Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the association between low ...
Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage
(MDPI, 2021-07-27)
[Abstract] Metal oxide nanoparticles (NPs) have a wide variety of applications in many consumer products and biomedical practices. As a result, human exposure to these nanomaterials is highly frequent, becoming an issue ...
Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y)
(2020)
[Abstrac] Titanium dioxide nanoparticles (TiO2 NPs) have a wide variety of applications in many consumer products, including as food additives, increasing the concern about the possible hazards that TiO2 NPs may pose to ...
DNA Damage in Circulating Leukocytes Measured With the Comet Assay May Predict the Risk of Death
(2021)
[Abstract] The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, ...
The hCOMET Project: International Database Comparison of Results with the Comet Assay in Human Biomonitoring. Baseline Frequency of DNA Damage and Effect of Main Confounders
(2021)
[Abstract] The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification ...
Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells
(2021)
[Abstract] Standard toxicity tests might not be fully adequate for evaluating nanomaterials since
their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block
micronucleus (CBMN) ...